Chemistry of 2-Aminoimidazoles

被引：6
|
作者：
Zula, Ales [1 ]
Kikelj, Danijel [1 ]
Ilas, Janez [1 ]
机构：
[1] Univ Ljubljana, Fac Pharm, Askerceva 7, Ljubljana 1000, Slovenia
来源：
JOURNAL OF HETEROCYCLIC CHEMISTRY | 2016年 / 53卷 / 02期
关键词：
BIOFILM FORMATION; SUBSTITUTED; 2-AMINOIMIDAZOLES; PRACTICAL SYNTHESIS; MARINE ALKALOIDS; INHIBITORS; OROIDIN; DERIVATIVES; CLATHRODIN; ANALOGS; POTENT;
D O I：
10.1002/jhet.2415
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
The 2-aminoimidazole (2-AI) ring is used widely as a building block in the design of new biologically active compounds, because of its good physico-chemical properties and potent activity in various test systems. Many marine alkaloids contain the 2-AI moiety. As a consequence, many synthetic routes have been developed in the total synthesis of natural compounds. The review covers all synthetic procedures for construction of 2-AI in particular and its analogs up to December 2014.
引用
收藏
页码：345 / 355
页数：11
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