Direct Oxidative Coupling of Enamides and 1,3-Dicarbonyl Compounds: A Facile and Versatile Approach to Dihydrofurans, Furans, Pyrroles, and Dicarbonyl Enamides

被引：69
|
作者：
Li, Pan [1 ,2 ]
Zhao, Jingjing [1 ]
Xia, Chungu [1 ]
Li, Fuwei [1 ]
机构：
[1] Chinese Acad Sci, Lanzhou Inst Chem Phys, State Key Lab Oxo Synth & Select Oxidat, Lanzhou 730000, Peoples R China
[2] Chinese Acad Sci, Grad Univ, Beijing 100049, Peoples R China
来源：
ORGANIC LETTERS | 2014年 / 16卷 / 22期
基金：
中国国家自然科学基金;
关键词：
CERIUM(IV) AMMONIUM-NITRATE; C-C; MANGANESE(III) ACETATE; VINYL AZIDES; METAL-SALTS; CYCLIZATION; STRATEGY; BONDS; ACYLATION; EFFICIENT;
D O I：
10.1021/ol503009f
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
An efficient manganese(III)-mediated oxidative coupling reaction between a-aryl enamides and 1,3-dicarbonyl compounds has been developed. A series of dihydrofurans and dicarbonyl enamides were synthesized in moderate to good yields. Moreover, these dihydrofurans could be readily transformed into the corresponding furans and pyrroles via the Paal-Knorr reaction.
引用
收藏
页码：5992 / 5995
页数：4
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