Recalcitrant pyoderma gangrenosum treated with thalidomide

被引：44
|
作者：
Federman, GL
Federman, DG
机构：
[1] Yale Univ, Sch Med, Dept Dermatol, New Haven, CT 06510 USA
[2] Yale Univ, Sch Med, Dept Med, New Haven, CT 06510 USA
来源：
MAYO CLINIC PROCEEDINGS | 2000年 / 75卷 / 08期
关键词：
D O I：
10.4065/75.8.842
中图分类号：
R5 [内科学];
学科分类号：
1002 ; 100201 ;
摘要：
Pyoderma gangrenosum is a painful, noninfectious, ulcerating skin disorder often associated with systemic disease. Thalidomide has been used to treat many inflammatory dermatologic conditions and has been reintroduced in the United States to treat immune-modulated diseases such as pyoderma gangrenosum. The patient described, a 47-year-old man, had histologically confirmed pyoderma gangrenosum that did not respond to treatment with several courses of methylprednisolone. The ulcer healed with 10 weeks of oral thalidomide administration.
引用
收藏
页码：842 / 844
页数：3
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