Gender-Associated Differences in Lung Cancer: Clinical Characteristics and Treatment Outcomes in Women

被引：44

作者：

Harichand-Herdt, Seema ^{[1
]}

Ramalingam, Suresh S. ^{[1
]}

机构：

[1] Emory Univ, Sch Med, Winship Canc Inst, Dept Hematol & Med Oncol, Atlanta, GA USA

来源：

SEMINARS IN ONCOLOGY | 2009年 / 36卷 / 06期

关键词：

SEX-ASSOCIATED DIFFERENCES; PROGNOSTIC-FACTORS; ESTROGEN-RECEPTOR; FEMALE-PATIENTS; PHASE-III; SURVIVAL; GEFITINIB; EPIDEMIOLOGY; CHEMOTHERAPY; PLUS;

D O I：

10.1053/j.seminoncol.2009.10.007

中图分类号：

R73 [肿瘤学];

学科分类号：

100214 ;

摘要：

Lung cancer is the leading cause of cancer deaths in the United States. In recent years the incidence of lung cancer in men has been declining, while in women it has been increasing. A number of population-based studies have demonstrated gender-based differences in clinical and pathologic factors, as well as in survival related to lung cancer. Disparities in age, smoking practices, and histological subtypes are among the differences that have been identified. Gender disparity also has been observed in outcomes, with improved survival observed for women in a number of clinical trials. This article reviews the gender-related differences in clinical and pathologic factors and outcomes of patients with lung cancer observed in population-based studies and clinical trials. Semin Oncol 36:572-580 (C) 2009 Elsevier Inc. All rights reserved.

引用

页码：572 / 580

页数：9

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