Fullerenols may find the widest application in science and technology. This causes particular interest in developing available and simple methods for the synthesis of water-soluble polyhydroxylated fullerene derivatives on an industrial scale as well as investigating the physicochemical and biological properties and principles of their application. This study systematizes the current literature data on the synthesis, physicochemical properties, and application of polyhydroxylated fullerenes (fullerenols), a class of water-soluble fullerene derivatives. The experimental and theoretical data presented in this study provide a comprehensive overview of these substances and can be valuable to specialists in the fields of nano technology, nanomaterials, and nanobiomedicine. (C) 2016 Published by Elsevier Ltd.
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Univ Castilla La Mancha, Fac Chem, Dept Chem Engn, E-13071 Ciudad Real, SpainUniv Castilla La Mancha, Fac Chem, Dept Chem Engn, E-13071 Ciudad Real, Spain
Nieto-Marquez, Antonio
Romero, Rubi
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Univ Autonoma Estado Mexico, Fac Chem, Toluca 50120, MexicoUniv Castilla La Mancha, Fac Chem, Dept Chem Engn, E-13071 Ciudad Real, Spain
Romero, Rubi
Romero, Amaya
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Univ Castilla La Mancha, Fac Chem, Dept Chem Engn, E-13071 Ciudad Real, SpainUniv Castilla La Mancha, Fac Chem, Dept Chem Engn, E-13071 Ciudad Real, Spain
Romero, Amaya
Valverde, Jose Luis
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Univ Castilla La Mancha, Fac Chem, Dept Chem Engn, E-13071 Ciudad Real, SpainUniv Castilla La Mancha, Fac Chem, Dept Chem Engn, E-13071 Ciudad Real, Spain
机构:
State Key Laboratory of Natural Medicines,Department of Pharmaceutics,School of Pharmacy,China Pharmaceutical UniversityState Key Laboratory of Natural Medicines,Department of Pharmaceutics,School of Pharmacy,China Pharmaceutical University
Minshan Guo
Xiaojie Sun
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State Key Laboratory of Natural Medicines,Department of Pharmaceutics,School of Pharmacy,China Pharmaceutical UniversityState Key Laboratory of Natural Medicines,Department of Pharmaceutics,School of Pharmacy,China Pharmaceutical University
Xiaojie Sun
Jiahui Chen
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State Key Laboratory of Natural Medicines,Department of Pharmaceutics,School of Pharmacy,China Pharmaceutical UniversityState Key Laboratory of Natural Medicines,Department of Pharmaceutics,School of Pharmacy,China Pharmaceutical University
Jiahui Chen
Ting Cai
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State Key Laboratory of Natural Medicines,Department of Pharmaceutics,School of Pharmacy,China Pharmaceutical UniversityState Key Laboratory of Natural Medicines,Department of Pharmaceutics,School of Pharmacy,China Pharmaceutical University