This research paper is about to examine the role of spin-off companies in research and development. The paper emphasizes the success factors (closeness to parent institutions, founder's competencies, life experience, R&D capacity, industrial concentration) in spin-off development. We introduce ELINOR Engineering Ltd., a Hungarian technology-oriented spin-off company, which can be seen as a good case for a successful spin-off company. The company initiated a new project in healthcare, which aims to develop duplex threaded fixing screw for more efficient curing of femoral fractures. The project is characterized by pronounced interdisciplinarity linking traumatology, technology engineering and business management. The paper shows the development of this project by emphasizing the success factors of spin-off companies.