Multiresidue method for the detection of tranquillisers, xylazine, and a β-blocker in animal production by liquid chromatography-tandem mass spectrometry

被引：0
|
作者：
Delahaut, P [1 ]
Brasseur, PY [1 ]
Dubois, M [1 ]
机构：
[1] CER, Lab Hormonol, B-6900 Marloie, Belgium
来源：
JOURNAL OF CHROMATOGRAPHY A | 2004年 / 1054卷 / 1-2期
关键词：
tranquillisers; xylazine; beta-blockers;
D O I：
10.1016/j.chroma.2004.08.094
中图分类号：
Q5 [生物化学];
学科分类号：
071010 ; 081704 ;
摘要：
Tranquillisers are often used in animal production, especially in pigs to calm them before transport to the slaughterhouse. The use of certain substances (derived from phenothiazine) is totally prohibited, whilst other compounds (butyrophenone and beta-blockers) are regulated through the establishment of MRLs. A physico-chemical detection method based on liquid chromatography-tandem mass spectrometry is described. Validation was carried out according to the criteria laid down in Directive 2002/657/EC. The method was also used to detect and quantify these substances in treated animals. (C) 2004 Elsevier B.V. All rights reserved.
引用
收藏
页码：373 / 378
页数：6
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