No tissue damage by chronic deep brain stimulation in Parkinson's disease

被引：1
|
作者：
Haberler, C
Alesch, F
Mazal, PR
Pilz, P
Jellinger, K
Pinter, MM
Hainfellner, JA
Budka, H
机构：
[1] Univ Vienna, Inst Neurol, A-1097 Vienna, Austria
[2] Univ Vienna, Dept Neurosurg, A-1010 Vienna, Austria
[3] Univ Vienna, Dept Clin Pathol, A-1010 Vienna, Austria
[4] Ludwig Boltzmann Inst Clin Neurobiol, Vienna, Austria
[5] Neurol Hosp Maria Theresien Schlossel, Vienna, Austria
[6] Landesnervenklin, Salzburg, Austria
来源：
ANNALS OF NEUROLOGY | 2000年 / 48卷 / 03期
关键词：
D O I：
10.1002/1531-8249(200009)48:3<372::AID-ANA12>3.0.CO;2-0
中图分类号：
R74 [神经病学与精神病学];
学科分类号：
摘要：
We report on the pathological findings in the brains of 8 Parkinson's disease patients treated with deep brain stimulation (DBS) of the thalamic ventral intermediate nucleus (6 cases) and subthalamic nucleus (2 cases). DBS was performed continuously for up to 70 months. AU brains showed well-preserved neural parenchyma and only mild gliosis around the lead track compatible with reactive changes due to surgical placement of the electrode. We conclude that chronic DBS does not cause damage to adjacent brain tissue.
引用
收藏
页码：372 / 376
页数：5
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