Modelling cytochrome P450 inhibition using large datasets of in vitro assays for CYP 2D6 and CYP 3A4

被引：0
|
作者：
Mao, B
Gozalbes, R
Barbosa, F
Migeon, J
Rogalski, S
Kamm, K
Wong, E
Costales, C
Shi, W
Froloff, N
Horvath, D
Wu, C
机构：
[1] Cerep Inc, Redmond, WA 98052 USA
[2] Cerep SA, F-92506 Rueil Malmaison, France
来源：
DRUG METABOLISM REVIEWS | 2004年 / 36卷
关键词：
D O I：
暂无
中图分类号：
R9 [药学];
学科分类号：
1007 ;
摘要：
686
引用
收藏
页码：343 / 343
页数：1
相关论文
共 50 条
  • [1] INHIBITION OF HUMAN CYTOCHROME P450 2D6 (CYP2D6) BY METHADONE
    WU, D
    OTTON, SV
    SPROULE, BA
    BUSTO, U
    INABA, T
    KALOW, W
    SELLERS, EM
    BRITISH JOURNAL OF CLINICAL PHARMACOLOGY, 1993, 35 (01) : 30 - 34
  • [2] RELATIONSHIP OF PASSIVE PERMEABILITY AND CYTOCHROME P450 (CYP) 3A4 INHIBITION
    Li, Ling
    Zhou, Julia
    Nouraldeen, Amr
    Wilson, Alan G. E.
    DRUG METABOLISM REVIEWS, 2014, 45 : 131 - 131
  • [3] Contribution of CYP 3A4 and CYP 2D6 in loratadine metabolism in vitro
    Dridi, D.
    Picard, N.
    Sauvage, F. L.
    Boughattas, N. A.
    Marquet, P.
    FUNDAMENTAL & CLINICAL PHARMACOLOGY, 2007, 21 : 44 - 44
  • [4] Cytochrome P450 2D6 and 3A4 enzyme inhibition by amine stimulants in dietary supplements
    Liu, Yitong
    Santillo, Michael F.
    DRUG TESTING AND ANALYSIS, 2016, 8 (3-4) : 307 - 310
  • [5] Hydroxychloroquine is Metabolized by Cytochrome P450 2D6, 3A4 and 2C8, and Inhibits Cytochrome P450 2D6, while its Metabolites also Inhibit Cytochrome P450 3A in vitro
    Paludetto, Marie-Noeurolle
    Kurkela, Mika
    Kahma, Helina
    Backman, Janne T.
    Niemi, Mikko
    Filppula, Anne M.
    DRUG METABOLISM AND DISPOSITION, 2023, 51 (03) : 293 - 305
  • [6] Effects of cytochrome (CYP) p450 3A4 inducers on CYP2B6 catalytic activity.
    Faucette, S
    Lindley, C
    Hawke, R
    Shord, S
    Clarke, M
    LeCluyse, E
    CLINICAL PHARMACOLOGY & THERAPEUTICS, 2001, 69 (02) : P10 - P10
  • [7] Inhibition of Human Cytochrome P450 Enzymes 3A4 and 2D6 by β-Carboline Alkaloids, Harmine Derivatives
    Zhao, Ting
    He, Yu-qi
    Wang, Jun
    Ding, Ke-min
    Wang, Chang-hong
    Wang, Zheng-tao
    PHYTOTHERAPY RESEARCH, 2011, 25 (11) : 1671 - 1677
  • [8] Cytochrome p450 2D6 (CYP2D6) inhibitory constituents of Catharanthus roseus
    Usia, T
    Watabe, T
    Kadota, S
    Tezuka, Y
    BIOLOGICAL & PHARMACEUTICAL BULLETIN, 2005, 28 (06) : 1021 - 1024
  • [9] Design and synthesis of a new fluorescent probe for cytochrome P450 3A4 (CYP 3A4)
    Chougnet, A
    Stoessel, C
    Woggon, WD
    BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2003, 13 (21) : 3643 - 3645
  • [10] Dose dependency of dextromethorphan for cytochrome P450 2D6 (CYP2D6) phenotyping
    Streetman, DS
    Ellis, RE
    Nafziger, AN
    Leeder, JS
    Gaedigk, A
    Gotschall, R
    Kearns, GL
    Bertino, JS
    CLINICAL PHARMACOLOGY & THERAPEUTICS, 1999, 66 (05) : 535 - 541
12345