3-(4-bromophenyl)-2,2-dimethyl-2,3-dihydroquinazolin-4(1H)-one

被引：2
|
作者：
Shi, DQ [1 ]
Li, ZY
Shi, CL
Zhuang, QY
Zhang, Y
机构：
[1] Xuzhou Normal Univ, Dept Chem, Xuzhou 221116, Peoples R China
[2] Key Lab Biotechnol Med Plants Jiangsu Prov, Xuzhou 221116, Peoples R China
[3] Suzhou Univ, Sch Chem & Chem Engn, Suzhou 215006, Peoples R China
来源：
ACTA CRYSTALLOGRAPHICA SECTION E-CRYSTALLOGRAPHIC COMMUNICATIONS | 2004年 / 60卷
关键词：
D O I：
10.1107/S1600536804025115
中图分类号：
O7 [晶体学];
学科分类号：
0702 ; 070205 ; 0703 ; 080501 ;
摘要：
The title compound, C16H15BrN2O, was synthesized by the reaction of N-(4-bromophenyl)-2-nitrobenzamide and acetone, induced by a low-valent titanium reagent (TiCl4/Zn). The dihydropyrimidine ring adopts a screw-boat conformation. The molecules are connected by N-H...O hydrogen bonds, forming a linear chain along the a axis.
引用
收藏
页码：O1992 / O1994
页数：3
相关论文
共 50 条
  • [1] 2-(4-Bromophenyl)-2-methyl-2,3-dihydroquinazolin-4(1H)-one
    Zhang, Mei-Mei
    Yang, Ke
    Wang, Xiang-Shan
    ACTA CRYSTALLOGRAPHICA SECTION E-STRUCTURE REPORTS ONLINE, 2010, 66 : O1069 - U1720
  • [2] Discovery and optimization of 1,7-disubstituted-2,2-dimethyl-2,3-dihydroquinazolin-4(1H)-ones as potent and selective PKCθ inhibitors
    Katoh, Taisuke
    Takai, Takafumi
    Yukawa, Takafumi
    Tsukamoto, Tetsuya
    Watanabe, Etsurou
    Mototani, Hideyuki
    Arita, Takeo
    Hayashi, Hiroki
    Nakagawa, Hideyuki
    Klein, Michael G.
    Zou, Hua
    Sang, Bi-Ching
    Snell, Gyorgy
    Nakada, Yoshihisa
    BIOORGANIC & MEDICINAL CHEMISTRY, 2016, 24 (11) : 2466 - 2475
  • [3] Photophysical properties of 2,3-dihydroquinazolin-4(1H)-one derivatives
    Cabrera-Rivera, Fanny A.
    Escalante, Jaime
    Morales-Rojas, Hugo
    Zigler, David F.
    Schmidt, Robert D.
    Jarocha, Lauren E.
    Forbes, Malcolm D. E.
    JOURNAL OF PHOTOCHEMISTRY AND PHOTOBIOLOGY A-CHEMISTRY, 2014, 294 : 31 - 37
  • [4] Synthesis and Crystal Structure of 3-(4-Methoxyphenyl)-2thioxo-2,3-dihydroquinazolin-4(1H)-one
    Saeed, Aamer
    ul Mahmood, Shams
    Ishida, H.
    CRYSTALS, 2011, 1 (03): : 171 - 177
  • [5] 2,2,7-Trimethyl-2,3-dihydroquinazolin-4(1H)-one
    Zhang, Ling
    Shi, Daxin
    Fan, Yanqiu
    Qian, Dongfeng
    Li, Jiarong
    ACTA CRYSTALLOGRAPHICA SECTION E-STRUCTURE REPORTS ONLINE, 2009, 65 : O1345 - U2447
  • [6] 2-(isopropylidenehydrazono)-3-methyl-2,3-dihydroquinazolin-4(1H)-one
    Kamali, Ahmad
    Sheikhshoaie, Iran
    Sharif, Mahboubeh A.
    Khavasi, Hamid Reza
    ACTA CRYSTALLOGRAPHICA SECTION E-CRYSTALLOGRAPHIC COMMUNICATIONS, 2007, 63 : O3612 - U4470
  • [7] A new concise synthesis of 2,3-dihydroquinazolin-4(1H)-one derivatives
    Desroses, Matthieu
    Scobie, Martin
    Helleday, Thomas
    NEW JOURNAL OF CHEMISTRY, 2013, 37 (11) : 3595 - 3597
  • [8] 2-(Biphenyl-4-yl)-2,3-dihydroquinazolin-4(1H)-one
    Chruszcz, Maksymilian
    Chinigo, Gary M.
    Capitosti, Scott M.
    Brown, Milton L.
    Minor, Wladek
    ACTA CRYSTALLOGRAPHICA SECTION E-STRUCTURE REPORTS ONLINE, 2007, 63 : O891 - O893
  • [9] 2-(2-Chlorophenyl)-2,3-dihydroquinazolin-4(1H)-one
    Li, Ming-Jian
    Feng, Chang-Jun
    ACTA CRYSTALLOGRAPHICA SECTION E-STRUCTURE REPORTS ONLINE, 2009, 65 : O2145 - U1949
  • [10] 2,3-Dihydroquinazolin-4(1H)-one as a privileged scaffold in drug design
    Badolato, Mariateresa
    Aiello, Francesca
    Neamati, Nouri
    RSC ADVANCES, 2018, 8 (37) : 20894 - 20921
12345