Indole alkaloids from cultivated Vinca major

被引:23
|
作者
Cheng, Gui-Guang [1 ,2 ]
Zhao, Yun-Li [1 ]
Zhang, Yu [1 ]
Lunga, Paul-Keilah [1 ,3 ]
Hu, Dong-Bao [1 ]
Li, Yan [1 ]
Gu, Ji [1 ]
Song, Chang-Wei [1 ]
Sun, Wei-Bang [1 ]
Liu, Ya-Ping [1 ]
Luo, Xiao-Dong [1 ]
机构
[1] Chinese Acad Sci, Kunming Inst Bot, State Key Lab Phytochem & Plant Resources West Ch, Kunming 650201, Peoples R China
[2] Kunming Univ Sci & Technol, Yunnan Inst Food Safety, Kunming 650500, Peoples R China
[3] Univ Yaounde I, Fac Sci, Dept Biochem, Lab Phytobiochem & Med Plants Study, Yaound, Cameroon
基金
中国国家自然科学基金;
关键词
Indole alkaloids; Cytotoxicity; Absolute configuration; Vinca major; NATURALLY OCCURRING SUBSTANCES; MAGNETIC-RESONANCE SPECTROSCOPY; STEM-BARK; MELODINUS-HENRYI; CONFORMATIONAL-ANALYSIS; (+)-SCHOLARISINE; MECHANISM; LEAVES; SEEDS; CAMPTOTHECIN;
D O I
10.1016/j.tet.2014.09.026
中图分类号
O62 [有机化学];
学科分类号
070303 ; 081704 ;
摘要
Nine new indole alkaloids, vinmajines A-I (1-9), and 43 known indole alkaloids were isolated from cultivated Vinca major in Kunming. The new structures were elucidated by extensive spectroscopic and quantum theory analysis. In addition, the results also supported that types of indole alkaloids from V. major might be influenced significantly by the ecological environment. (C) 2014 Elsevier Ltd. All rights reserved.
引用
收藏
页码:8723 / 8729
页数:7
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