Novel T790M mutant-selective EGFR kinase inhibitors

被引：0
|
作者：
不详
机构：
来源：
PHARMACOGENOMICS | 2010年 / 11卷 / 06期
关键词：
D O I：
暂无
中图分类号：
R9 [药学];
学科分类号：
1007 ;
摘要：
引用
收藏
页码：744 / 744
页数：1
相关论文
共 50 条
  • [1] Novel mutant-selective EGFR kinase inhibitors against EGFR T790M
    Zhou, Wenjun
    Ercan, Dalia
    Chen, Liang
    Yun, Cai-Hong
    Li, Danan
    Capelletti, Marzia
    Cortot, Alexis B.
    Chirieac, Lucian
    Iacob, Roxana E.
    Padera, Robert
    Engen, John R.
    Wong, Kwok-Kin
    Eck, Michael J.
    Gray, Nathanael S.
    Jaenne, Pasi A.
    NATURE, 2009, 462 (7276) : 1070 - 1074
  • [2] Novel mutant-selective EGFR kinase inhibitors against EGFR T790M
    Wenjun Zhou
    Dalia Ercan
    Liang Chen
    Cai-Hong Yun
    Danan Li
    Marzia Capelletti
    Alexis B. Cortot
    Lucian Chirieac
    Roxana E. Iacob
    Robert Padera
    John R. Engen
    Kwok-Kin Wong
    Michael J. Eck
    Nathanael S. Gray
    Pasi A. Jänne
    Nature, 2009, 462 : 1070 - 1074
  • [3] Overcoming EGFR(T790M) and EGFR(C797S) resistance with mutant-selective allosteric inhibitors
    Jia, Yong
    Yun, Cai-Hong
    Park, Eunyoung
    Rcan, Dalia E.
    Manuia, Mari
    Juarez, Jose
    Xu, Chunxiao
    Rhee, Kevin
    Chen, Ting
    Zhang, Haikuo
    Palakurthi, Sangeetha
    Jang, Jaebong
    Lelais, Gerald
    DiDonato, Michael
    Bursulaya, Badry
    Michellys, Pierre-Yves
    Epple, Robert
    Marsilje, Thomas H.
    McNeill, Matthew
    Lu, Wenshuo
    Harris, Jennifer
    Bender, Steven
    Wong, Kwok-Kin
    Janne, Pasi A.
    Eck, Michael J.
    NATURE, 2016, 534 (7605) : 129 - +
  • [4] Overcoming EGFR(T790M) and EGFR(C797S) resistance with mutant-selective allosteric inhibitors
    Yong Jia
    Cai-Hong Yun
    Eunyoung Park
    Dalia Ercan
    Mari Manuia
    Jose Juarez
    Chunxiao Xu
    Kevin Rhee
    Ting Chen
    Haikuo Zhang
    Sangeetha Palakurthi
    Jaebong Jang
    Gerald Lelais
    Michael DiDonato
    Badry Bursulaya
    Pierre-Yves Michellys
    Robert Epple
    Thomas H. Marsilje
    Matthew McNeill
    Wenshuo Lu
    Jennifer Harris
    Steven Bender
    Kwok-Kin Wong
    Pasi A. Jänne
    Michael J. Eck
    Nature, 2016, 534 : 129 - 132
  • [5] Molecular Dynamics Analysis of Binding of Kinase Inhibitors to WT EGFR and the T790M Mutant
    Park, Jiyong
    McDonald, Joseph J.
    Petter, Russell C.
    Houk, K. N.
    JOURNAL OF CHEMICAL THEORY AND COMPUTATION, 2016, 12 (04) : 2066 - 2078
  • [6] Identification of a novel nitroflavone-based scaffold for designing mutant-selective EGFR tyrosine kinase inhibitors targeting T790M and C797S resistance in advanced NSCLC
    Cristina, Minnelli
    Emiliano, Laudadio
    Leonardo, Sorci
    Giulia, Sabbatini
    Roberta, Galeazzi
    Adolfo, Amici
    Marta, Semrau S.
    Paola, Storici
    Samuele, Rinaldi
    Pierluigi, Stipa
    Massimo, Marcaccio
    Giovanna, Mobbili
    BIOORGANIC CHEMISTRY, 2022, 129
  • [7] Selective pressure for the EGFR T790M resistance mutation may be different for different EGFR tyrosine kinase inhibitors
    Chmielecki, Juliann
    Pietanza, Maria C.
    Kris, Mark
    Miller, Vincent
    Pao, William
    JOURNAL OF THORACIC ONCOLOGY, 2010, 5 (06) : S250 - S250
  • [8] BPI-7701, a Covalent Mutant-Selective EGFR Inhibitor, Inhibits the Growth of NSCLC Lines with EGFR Activating and T790M Resistance Mutations
    Wilde, Victoria L.
    Zhang, Don X.
    Peng, Jirong
    Greco, Michael N.
    Green, Michael A.
    Costanzo, Michael J.
    JOURNAL OF THORACIC ONCOLOGY, 2015, 10 (09) : S526 - S527
  • [9] Pyridones as Highly Selective, Noncovalent Inhibitors of T790M Double Mutants of EGFR
    Bryan, Marian C.
    Burdick, Daniel J.
    Chan, Bryan K.
    Chen, Yuan
    Clausen, Saundra
    Dotson, Jennafer
    Eigenbrot, Charles
    Elliott, Richard
    Hanan, Emily J.
    Heald, Robert
    Jackson, Philip
    La, Hank
    Lainchbury, Michael
    Malek, Shiva
    Mann, Sam E.
    Purkey, Hans E.
    Schaefer, Gabriele
    Schmidt, Stephen
    Seward, Eileen
    Sideris, Steve
    Wang, Shumei
    Yen, Ivana
    Yu, Christine
    Heffron, Timothy P.
    ACS MEDICINAL CHEMISTRY LETTERS, 2016, 7 (01): : 100 - 104
  • [10] Mutant-Selective Irreversible EGFR Inhibitor, Naquotinib, Inhibits Tumor Growth in NSCLC Models with EGFR-Activating Mutations, T790M Mutation, and AXL Overexpression
    Tanaka, Hiroaki
    Sakagami, Hideki
    Kaneko, Naoki
    Konagai, Satoshi
    Yamamoto, Hiroko
    Matsuya, Takahiro
    Yuri, Masatoshi
    Yamanaka, Yosuke
    Mori, Masamichi
    Takeuchi, Masahiro
    Koshio, Hiroyuki
    Hirano, Masaaki
    Kuromitsu, Sadao
    MOLECULAR CANCER THERAPEUTICS, 2019, 18 (08) : 1366 - 1373
12345