Managing large bone defects in children: a systematic review of the 'induced membrane technique'

被引：19

作者：

Morelli, Ilaria ^{[1
,2
,4
]}

Drago, Lorenzo ^{[3
,4
]}

George, David A. ^{[5
]}

Romano, Delia ^{[1
,2
]}

Romano, Carlo L. ^{[1
,2
]}

机构：

[1] IRCCS Galeazzi Orthopaed Inst, Dept Reconstruct Surg, Via R Galeazzi 4, I-20161 Milan, Italy

[2] IRCCS Galeazzi Orthopaed Inst, Osteoarticular Infect CRIO Unit, Via R Galeazzi 4, I-20161 Milan, Italy

[3] IRCCS Galeazzi Orthopaed Inst, Lab Clin Chem & Microbiol, Milan, Italy

[4] Univ Milan, Milan, Italy

[5] Univ Coll London Hosp, Dept Trauma & Orthopaed, London, England

来源：

JOURNAL OF PEDIATRIC ORTHOPAEDICS-PART B | 2018年 / 27卷 / 05期

关键词：

bone defect; bone nonunion treatment; children; induced membrane technique; Masquelet technique; osteomyelitis; paediatric; systematic review; VASCULARIZED FIBULAR GRAFT; TUMOR RESECTION; CONGENITAL PSEUDOARTHROSIS; BIOLOGICAL RECONSTRUCTION; MASQUELET TECHNIQUE; SKELETAL DEFECTS; TIBIAL DEFECTS; CASE SERIES; LONG BONES; FOLLOW-UP;

D O I：

10.1097/BPB.0000000000000456

中图分类号：

R826.8 [整形外科学]; R782.2 [口腔颌面部整形外科学]; R726.2 [小儿整形外科学]; R62 [整形外科学（修复外科学）];

学科分类号：

摘要：

Thirty years after its description by Masquelet in 1986, this is the first systematic review aiming to critically evaluate the 'induced membrane technique' effectiveness in achieving bone union in children. Only six papers fulfilled our inclusion criteria (54 patients). The relatively small number of reported cases did not allow a formal meta-analysis. The tibia was the most involved bone. Most frequent aetiologies were congenital pseudoarthrosis and tumour resections. Although effective in achieving bone healing in similar to 91% of the patients (bone defects <= 24 cm long), the induced membrane technique was associated with a high rate of complications (54% of patients). Level of Evidence: IV. Copyright (C) 2018 Wolters Kluwer Health, Inc. All rights reserved.

引用

页码：443 / 455

页数：13

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