Biocompatible Europium Doped Hydroxyapatite Nanoparticles as a Biological Fluorescent Probe

被引：40

作者：

Han, Yingchao ^{[1
]}

Wang, Xinyu ^{[1
]}

Li, Shipu ^{[1
]}

机构：

[1] Wuhan Univ Technol, Biomed Mat & Engn Res Ctr, Wuhan 430070, Peoples R China

来源：

CURRENT NANOSCIENCE | 2010年 / 6卷 / 02期

关键词：

Europium doped hydroxyapatite; Inorganic nanoparticles; Cell labelling; Fluorescent probe; GEL COMBUSTION METHOD; QUANTUM DOTS; CELLS; POWDERS; ROUTE; CDSE; DNA;

D O I：

10.2174/157341310790945632

中图分类号：

Q81 [生物工程学（生物技术）]; Q93 [微生物学];

学科分类号：

071005 ; 0836 ; 090102 ; 100705 ;

摘要：

In this study, a cell labelling method is presented using biocompatible europium doped hydroxyapatite (Eu-HAP) inorganic nanoparticles. Eu-HAP nanoparticles were successfully prepared by precipitation method and utilized to label Bel-7402 human liver cancer cells as fluorescent probe. After Eu-HAP nanoparticles were internalized by cells, the strong green fluorescence and the red fluorescence were observed with excitation of blue light and green light respectively. Results show that the Eu-HAP nanoparticles exhibit the potential to become valuable biocompatible fluorescent labelling material in biological studies.

引用

页码：178 / 183

页数：6

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