Platelet CD36 Induces ERK5 Activation through a Redox-Regulated Signaling Pathway to Promote a Prothrombotic Phenotype

被引：0
|
作者：
Yang, Moua [1 ,2 ]
Vasquez-Vivar, Jeannette M. [3 ]
Chen, Yiliang [2 ]
Cameron, Scott J. [4 ]
Morrell, Craig N. [4 ]
Silverstein, Roy L. [2 ,5 ]
机构：
[1] Med Coll Wisconsin, Dept Cell Biol Neurobiol & Anat, Milwaukee, WI 53226 USA
[2] Blood Ctr SE Wisconsin Inc, Blood Res Inst, Milwaukee, WI 53233 USA
[3] Med Coll Wisconsin, Dept Biophys, Milwaukee, WI 53226 USA
[4] Univ Rochester, Sch Med, Aab Cardiovasc Res Inst, Rochester, NY USA
[5] Med Coll Wisconsin, Dept Med, Milwaukee, WI 53226 USA
来源：
BLOOD | 2015年 / 126卷 / 23期
关键词：
D O I：
暂无
中图分类号：
R5 [内科学];
学科分类号：
1002 ; 100201 ;
摘要：
引用
收藏
页数：3
相关论文
共 22 条
  • [1] Platelet CD36 promotes thrombosis by activating redox sensor ERK5 in hyperlipidemic conditions
    Yang, Moua
    Cooley, Brian C.
    Li, Wei
    Chen, Yiliang
    Vasquez-Vivar, Jeannette
    Scoggins, Na'il O.
    Cameron, Scott J.
    Morrell, Craig N.
    Silverstein, Roy L.
    BLOOD, 2017, 129 (21) : 2917 - 2927
  • [2] CD36 Promotes Platelet Phosphatidylserine Exposure through MAP Kinase ERK5
    Yang, Moua
    Kholmukhamedov, Andaleb
    Scoggins, Na'il O.
    Cooley, Brian C.
    Morrell, Craig
    Jobe, Shawn M.
    Silverstein, Roy L.
    BLOOD, 2017, 130
  • [3] Platelet CD36 signaling through ERK5 promotes caspase-dependent procoagulant activity and fibrin deposition in vivo
    Yang, Moua
    Kholmukhamedov, Andaleb
    Schulte, Marie L.
    Cooley, Brian C.
    Scoggins, Na'il O.
    Wood, Jeremy P.
    Cameron, Scott J.
    Morrell, Craig N.
    Jobe, Shawn M.
    Silverstein, Roy L.
    BLOOD ADVANCES, 2018, 2 (21) : 2848 - 2861
  • [4] Platelet CD36 Potentiates Thrombus Formation in Hyperlipidemic Conditions By Activating Redox Sensitive MAP Kinase ERK5
    Yang, Moua
    Cooley, Brian C.
    Chen, Yiliang
    Vasquez-Vivar, Jeannette M.
    Scoggins, Na'il O.
    Cameron, Scott J.
    Morrell, Craig N.
    Silverstein, Roy L.
    BLOOD, 2016, 128 (22)
  • [5] CD36 and ERK5 link dyslipidemia to apoptotic-like platelet procoagulant function
    Yang, Moua
    Silverstein, Roy L.
    CURRENT OPINION IN HEMATOLOGY, 2019, 26 (05) : 357 - 365
  • [6] Oxidized LDL Induces Alternative Macrophage Phenotype through Activation of CD36 and PAFR
    Rios, Francisco J.
    Koga, Marianna M.
    Pecenin, Mateus
    Ferracini, Matheus
    Gidlund, Magnus
    Jancar, S.
    MEDIATORS OF INFLAMMATION, 2013, 2013
  • [7] EphrinB-EphB Signaling Induces Hyperalgesia through ERK5/CREB Pathway in Rats
    Yu, Li-Na
    Sun, Li-Hong
    Wang, Min
    Wang, Lie-Ju
    Wu, Ying
    Yu, Jing
    Wang, Wen-Na
    Zhang, Feng-Jiang
    Li, Xue
    Yan, Min
    PAIN PHYSICIAN, 2017, 20 (04) : E563 - E574
  • [8] Platelet CD36 Promotes ERK5 and Caspase-Dependent Procoagulant Phosphatidylserine Externalization and In Vivo Fibrin Formation in Dyslipidemia
    Yang, Moua
    Kholmukhamedov, Andaleb
    Schulte, Marie L.
    Cooley, Brian C.
    Scoggins, Na'il O.
    Wood, Jeremy P.
    Cameron, Scott J.
    Morrell, Craig
    Jobe, Shawn M.
    Silverstein, Roy L.
    BLOOD, 2018, 132
  • [9] Naoxintong capsule limits myocardial infarct expansion by inhibiting platelet activation through the ERK5 pathway
    Zhang, Lusha
    Chen, Lu
    You, Xingyu
    Li, Mengyao
    Shi, Hong
    Sun, Wei
    Leng, Yuze
    Xue, Yuejin
    Wang, Hong
    PHYTOMEDICINE, 2022, 98
  • [10] Qilong capsule prevents myocardial ischemia/reperfusion injury by inhibiting platelet activation via the platelet CD36 signaling pathway
    Wang, Min
    Li, Lingxu
    Tang, Shuang
    Liu, Jianxun
    Liu, Shusen
    Ye, Jingxue
    Ding, Gang
    Sun, Guibo
    JOURNAL OF ETHNOPHARMACOLOGY, 2024, 330
123