The process of image registration and fusion is used to obtain a resultant image with better characteristics. The concept of image registration and fusion can be used in various domains such as remote sensing, satellite imaging, medical imaging, etc. But, as the smallest of errors can have great consequences in medical images, applying these concepts in medical imaging will make a great difference. Aligning images spatially into one single framework is attained through image registration. There are various methods or techniques to implement image registration. Landmark registration, a semi-automatic registration method is used where images are spatially aligned by selecting control points from both the images and applying geometric transformation that helps in translation, rotation, scaling and shearing. During fusion process intermixing of traits from source images is performed using Discrete Wavelet Transform and Bicubic interpolation. The resultant image helps the doctors for better clinical diagnosis.