Eco-friendly C-3 Selenation of Imidazo[1,2-a]pyridines in Ionic Liquid

被引：14
|
作者：
Wang, Xin [1 ]
Mu, Shiqiang [1 ]
Sun, Ting [1 ]
Sun, Kai [1 ]
机构：
[1] Anyang Normal Univ, Coll Chem & Chem Engn, Anyang 455000, Peoples R China
来源：
CHINESE JOURNAL OF ORGANIC CHEMISTRY | 2019年 / 39卷 / 10期
基金：
中国国家自然科学基金;
关键词：
selenation; imidazo[1,2-a]pyridines; C-3; functionalization; electrophilic mechanism; DIRECT ARYLATION; SELENIUM POWDER; IMIDAZOHETEROCYCLES; SULFENYLATION; EFFICIENT; CATALYST; ORGANOSELENIUM; CHALCOGENATION; THIOCYANATION; BROMIDES;
D O I：
10.6023/cjoc201904057
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
An relative eco-friendly protocol for the direct C-3 selenation of imidazo[1,2-a]pyridines with vorious organoselenides has been developed, gaving the desired products in moderate to excellent yields. Preliminary experimental results are consistent with a C-3 electrophilic functionalization mechanism. The features with relative green reaction conditions, broad substrate scope, and easy scale-up operation would make this strategy promising and important for the preparation of nitrogen and selenium containing molecules.
引用
收藏
页码：2802 / 2807
页数：6
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