Median treatment effect in randomized trials

被引:15
|
作者
Lee, MJ [1 ]
机构
[1] Univ Tsukuba, Inst Policy & Planning Sci, Tsukuba, Ibaraki 3058573, Japan
关键词
exchangeability; median; treatment effect;
D O I
10.1111/1467-9868.00253
中图分类号
O21 [概率论与数理统计]; C8 [统计学];
学科分类号
020208 ; 070103 ; 0714 ;
摘要
For two response variables y(t) and y(c) corresponding to two treatments (or two policies) T and C, we wish to learn about quantiles of y(t) - y(c) from the marginal quantiles of y(t) and y(c); only one of y(t) and y(c) is observed for an individual. We find that, in general, this is difficult for quantiles other than the median unless strong assumptions are imposed on how y(t) is related to y(c). For the median, we present conditions under which the sign of the median treatment effect is identified.
引用
收藏
页码:595 / 604
页数:10
相关论文
共 50 条
  • [1] BIASED ESTIMATES OF TREATMENT EFFECT IN RANDOMIZED TRIALS
    GAIL, M
    WIEAND, S
    PIANTADOSI, S
    CONTROLLED CLINICAL TRIALS, 1984, 5 (03): : 303 - 303
  • [2] TESTS FOR NO TREATMENT EFFECT IN RANDOMIZED CLINICAL-TRIALS
    GAIL, MH
    TAN, WY
    PIANTADOSI, S
    BIOMETRIKA, 1988, 75 (01) : 57 - 64
  • [3] Assessment of Treatment Effect Heterogeneity for Multiregional Randomized Clinical Trials
    Zhuang, Haotian
    Wang, Xiaofei
    George, Stephen L.
    STATISTICS IN BIOPHARMACEUTICAL RESEARCH, 2024,
  • [4] Comparing algorithms for characterizing treatment effect heterogeneity in randomized trials
    Sun, Sophie
    Sechidis, Konstantinos
    Chen, Yao
    Lu, Jiarui
    Ma, Chong
    Mirshani, Ardalan
    Ohlssen, David
    Vandemeulebroecke, Marc
    Bornkamp, Bjoern
    BIOMETRICAL JOURNAL, 2024, 66 (01)
  • [5] Treatment effect heterogeneity in blocked randomized trials with binary outcomes
    Albert, JM
    Gadbury, GL
    CONTROLLED CLINICAL TRIALS, 2003, 24 : 56S - 57S
  • [6] Inference for the treatment effect in longitudinal cluster randomized trials when treatment effect heterogeneity is ignored
    Bowden, Rhys
    Forbes, Andrew B.
    Kasza, Jessica
    STATISTICAL METHODS IN MEDICAL RESEARCH, 2021, 30 (11) : 2503 - 2525
  • [7] Instrumental variable estimation of early treatment effect in randomized screening trials
    Saha, Sudipta
    Liu, Zhihui
    Saarela, Olli
    LIFETIME DATA ANALYSIS, 2021, 27 (04) : 537 - 560
  • [8] Preventing false discovery of heterogeneous treatment effect subgroups in randomized trials
    Joseph Rigdon
    Michael Baiocchi
    Sanjay Basu
    Trials, 19
  • [9] Instrumental variable estimation of early treatment effect in randomized screening trials
    Sudipta Saha
    Zhihui Liu
    Olli Saarela
    Lifetime Data Analysis, 2021, 27 : 537 - 560
  • [10] Hierarchical Bayes Approach to Estimate the Treatment Effect for Randomized Controlled Trials
    Liang, Xinya
    Kamata, Akihito
    Li, Ji
    EDUCATIONAL AND PSYCHOLOGICAL MEASUREMENT, 2020, 80 (06) : 1090 - 1114