Microwave-assisted FLP-catalyzed hydrogenations

被引：14
|
作者：
Tussing, S. [1 ]
Paradies, J. [1 ]
机构：
[1] Univ Paderborn, Inst Organ Chem, Warburger Str 100, D-33098 Paderborn, Germany
来源：
DALTON TRANSACTIONS | 2016年 / 45卷 / 14期
关键词：
FRUSTRATED LEWIS PAIRS; HETEROLYTIC DIHYDROGEN ACTIVATION; METAL-FREE HYDROGENATION; ENANTIOSELECTIVE HYDROGENATION; ASYMMETRIC HYDROGENATION; IMINES; REDUCTION;
D O I：
10.1039/c5dt03857j
中图分类号：
O61 [无机化学];
学科分类号：
070301 ; 081704 ;
摘要：
FLP-catalyzed hydrogenations of 15 substrates were compared using microwave irradiation and conventional heating. The direct comparison revealed that a rate acceleration of up to 2.5 was achieved in the presence of microwaves. This heating method is particularly promising for the hydrogenation of nitrogen-containing heterocycles. Acridine, quinines and especially 1-methyl indole were reduced very efficiently under mild conditions and only 4 bar hydrogen pressure in high yields.
引用
收藏
页码：6124 / 6128
页数：5
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