Detection of chromosome 15 deletion in Prader-Willi syndrome using fluorescence in situ hybridization

被引：0
|
作者：
Suzuki, Y [1 ]
Sasagawa, I [1 ]
Yazawa, H [1 ]
Tateno, T [1 ]
Nakada, T [1 ]
机构：
[1] Yamagata Univ, Sch Med, Dept Urol, Yamagata 9909585, Japan
来源：
ARCHIVES OF ANDROLOGY | 2000年 / 45卷 / 01期
关键词：
chromosome analysis; fluorescence in situ hybridization; Prader-Willi syndrome;
D O I：
暂无
中图分类号：
R69 [泌尿科学（泌尿生殖系疾病）];
学科分类号：
摘要：
Deletion of chromosome 15 was investigated in 6 patients with Prader-Willi syndrome (PWS) using chromsome and fluorescence in situ hybridization (FISH) analysis. Although chromosome analysis using G-banding methods revealed the deletion of 15q11-q13 in only 3 cases, staining by FISH using D15S11 and/or small nuclear ribonucleoprotein polypeptide N (SNRPN) probes detected chromosome 15 deletion in all cases. It would appear that FISH analysis is an effective diagnostic test for the detection of chromosome 15 deletion in patients with PWS.
引用
收藏
页码：13 / 17
页数：5
相关论文
共 50 条
  • [1] CHROMOSOME-15 DELETION IN THE PRADER-WILLI SYNDROME
    FORD, JH
    SHEFFIELD, LJ
    WHITE, DI
    PATHOLOGY, 1983, 15 (01) : 104 - 104
  • [2] Maternal chromosome 15 deletion in a case of Prader-willi syndrome
    Batstone, Paul
    Forsyth, L. A.
    Cooke, A.
    JOURNAL OF MEDICAL GENETICS, 2008, 45 : S92 - S92
  • [3] PRADER-WILLI SYNDROME ASSOCIATED WITH AN INTERSTITIAL DELETION OF CHROMOSOME 15
    BONUCCELLI, CM
    STETTEN, G
    LEVITT, RC
    LEVIN, LS
    PYERITZ, RE
    JOHNS HOPKINS MEDICAL JOURNAL, 1982, 151 (05): : 237 - 242
  • [4] Mosaicism in Prader-Willi syndrome: Detection using fluorescent in situ hybridization
    Golden, WL
    Sudduth, KW
    Burnett, SH
    Kelly, TE
    AMERICAN JOURNAL OF MEDICAL GENETICS, 1999, 85 (04): : 424 - 425
  • [5] A CASE OF THE PRADER-WILLI SYNDROME HAVING THE INTERSTITIAL DELETION OF NO 15 CHROMOSOME
    KADOTANI, T
    WATANABE, Y
    KANATA, S
    KUMADA, T
    TAKEMURA, I
    PROCEEDINGS OF THE JAPAN ACADEMY SERIES B-PHYSICAL AND BIOLOGICAL SCIENCES, 1986, 62 (10): : 405 - 407
  • [6] PATERNAL ORIGIN OF CHROMOSOME-15 DELETION IN PRADER-WILLI SYNDROME
    BUTLER, MG
    PALMER, CG
    AMERICAN JOURNAL OF HUMAN GENETICS, 1983, 35 (06) : A128 - A128
  • [7] PARENTAL ORIGIN OF CHROMOSOME-15 DELETION IN PRADER-WILLI SYNDROME
    BUTLER, MG
    PALMER, CG
    LANCET, 1983, 1 (8336): : 1285 - 1286
  • [8] CHROMOSOME-15 AND PRADER-WILLI SYNDROME
    ZUFFARDI, O
    BUHLER, EM
    FRACCARO, M
    CLINICAL GENETICS, 1978, 14 (05) : 315 - 316
  • [9] CHROMOSOME-15 IN PRADER-WILLI SYNDROME
    FEAR, CN
    MUTTON, DE
    BERRY, AC
    HECKMATT, JZ
    DUBOWITZ, V
    DEVELOPMENTAL MEDICINE AND CHILD NEUROLOGY, 1985, 27 (03): : 305 - 311
  • [10] THE PRADER-WILLI SYNDROME AND INTERSTITIAL DELETION OF CHROMOSOME 15 - HIGH-RESOLUTION CHROMOSOME ANALYSES OF 14 PATIENTS WITH THE PRADER-WILLI SYNDROME AND OF 5 SUSPECTED INFANTS
    FUKUSHIMA, Y
    NIIKAWA, N
    KUROKI, Y
    JAPANESE JOURNAL OF HUMAN GENETICS, 1984, 29 (01): : 1 - 6
12345