Reactivity of 3-iodoimidazo[1,2-a]pyridines using a Suzuki-type cross-coupling reaction

被引：102
|
作者：
Enguehard, C
Renou, JL
Collot, V
Hervet, M
Rault, S
Gueiffier, A
机构：
[1] UFR Sci Pharmaceut, Chim Therapeut Lab, F-37200 Tours, France
[2] Ctr Etud & Rech Medicament Normandie, UFR Sci Pharmaceut, F-14032 Caen, France
来源：
JOURNAL OF ORGANIC CHEMISTRY | 2000年 / 65卷 / 20期
关键词：
D O I：
10.1021/jo000698z
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
The influence of base and solvent in Suzuki cross-coupling reaction on various 2-substituted-3-iodbimidazo[1,2-a]pyridines was reported. The reactivity was largely influenced by nature of the substituent. Optimized yields and shortened times of reaction were obtained using strong bases in DME.
引用
收藏
页码：6572 / 6575
页数：4
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