CELL BIOLOGY Ubiquitination without E1 and E2 enzymes

被引：22
|
作者：
Bhogaraju, Sagar [1 ,2 ]
Dikic, Ivan [1 ,2 ]
机构：
[1] Goethe Univ Frankfurt, Inst Biochem 2, Sch Med, D-60590 Frankfurt, Germany
[2] Goethe Univ Frankfurt, Buchmann Inst Mol Life Sci, D-60590 Frankfurt, Germany
来源：
NATURE | 2016年 / 533卷 / 7601期
关键词：
LEGIONELLA-PNEUMOPHILA; SYSTEM;
D O I：
10.1038/nature17888
中图分类号：
O [数理科学和化学]; P [天文学、地球科学]; Q [生物科学]; N [自然科学总论];
学科分类号：
07 ; 0710 ; 09 ;
摘要：
A protein in the pathogenic bacterium Legionella pneumophila has been found to attach the modifying molecule ubiquitin to human proteins, using a mechanism that, surprisingly, does not involve cellular E1 and E2 enzymes. See Letter p.120
引用
收藏
页码：43 / 44
页数：2
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