Isoniazid prophylaxis in lung transplantation

被引:20
|
作者
Roman, A
Bravo, C
Levy, G
Monforte, V
Vidal, R
Solé, J
Maestre, J
Morell, F
机构
[1] Hosp Gen Valle Hebron, Serv Pneumol, Barcelona 08035, Spain
[2] Hosp Gen Valle Hebron, Serv Cirurgia Torac, Barcelona, Spain
来源
JOURNAL OF HEART AND LUNG TRANSPLANTATION | 2000年 / 19卷 / 09期
关键词
D O I
10.1016/S1053-2498(00)00163-7
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
The incidence of tuberculous disease (TD) is higher in lung-transplant patients than in the general population. During a 7-year period, we included 61 patients who underwent lung transplantation in a prospective isoniazid prophylaxis protocol. Isoniazid was prescribed to infected and anergic patients not previously treated when added to the waiting list. Six of 61 patients (10%) developed tuberculosis. We observed no differences in tuberculous disease incidence between infected-anergic and non-infected patients. In our tuberculous-endemic area, isoniazid prophylaxis is safe and offers protection from TD to infected and anergic patients who must be enrolled in a lung transplantation program.
引用
收藏
页码:903 / 906
页数:4
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