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Neurologic Manifestations of Systemic Lupus Erythematosus in Children and Adults
被引:154
|作者:
Muscal, Eyal
[2
]
Brey, Robin L.
[1
]
机构:
[1] Univ Texas Hlth Sci Ctr San Antonio, Dept Neurol, San Antonio, TX 78229 USA
[2] Baylor Coll Med, Div Pediat Rheumatol, Texas Childrens Hosp, Houston, TX 77030 USA
关键词:
Collagen vascular disease;
Systemic lupus erythematosus;
Neurologic disease;
Autoantibodies;
Cognitive dysfunction;
INTERNATIONAL INCEPTION COHORT;
STEM-CELL TRANSPLANTATION;
BLOOD-BRAIN-BARRIER;
NEUROPSYCHIATRIC MANIFESTATIONS;
CHILDHOOD-ONSET;
WHITE-MATTER;
COGNITIVE DYSFUNCTION;
AUTOIMMUNE-DISEASE;
NMDA RECEPTORS;
ANTIBODIES;
D O I:
10.1016/j.ncl.2009.09.004
中图分类号:
R74 [神经病学与精神病学];
学科分类号:
摘要:
Among the collagen vascular diseases neurologic manifestations have been most commonly recognized and well-studied in systemic lupus erythematosus (SLE, lupus). Neurologic manifestations are less prevalent in other systemic inflammatory and autoimmune disorders. This review focuses on the clinical presentation, pathophysiology, and treatment strategies of neuropsychiatric lupus (NPSLE) in children and adults.
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页码:61 / +
页数:14
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