Diffusion Imaging for Therapy Response Assessment of Brain Tumor

被引：40

作者：

Chenevert, Thomas L. ^{[1
]}

Ross, Brian D. ^{[1
]}

机构：

[1] Univ Michigan, Med Ctr, Dept Radiol, Ann Arbor, MI 48109 USA

来源：

NEUROIMAGING CLINICS OF NORTH AMERICA | 2009年 / 19卷 / 04期

基金：

美国国家卫生研究院;

关键词：

Diffusion-weighted MRI; Apparent diffusion coefficient; Diffusion anisotropy; Brain tumor; Treatment response; Parametric response map; MALIGNANT GLIOMA PATIENTS; WATER DIFFUSION; WHITE-MATTER; RADIATION-THERAPY; TENSOR; GRADE; MAP; ANISOTROPY; BIOMARKER; MODEL;

D O I：

10.1016/j.nic.2009.08.009

中图分类号：

Q189 [神经科学];

学科分类号：

071006 ;

摘要：

Advanced imaging provides insight into biophysical, physiologic, metabolic, or functional properties of tissues. Because water mobility is sensitive to cellular homeostasis, cellular density, and microstructural organization, it is considered a valuable tool in the advanced imaging arsenal. This article summarizes diffusion imaging concepts and highlights clinical applications of diffusion MR imaging for oncologic imaging. Diffusion tensor imaging and its derivative maps of diffusion anisotropy allow assessment of tumor compression or destruction of adjacent normal tissue anisotropy and may aid to assess tumor infiltration and aid presurgical planning.

引用

页码：559 / +

页数：14

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