A unique C-linked chalcone-dihydrochalcone dimer from Dracaena cinnabari resin

被引：8
|
作者：
Helal, Iman E. [1 ]
Elsbaey, Marwa [1 ]
Zaghloul, Ahmed M. [1 ]
Mansour, El-Sayed S. [1 ]
机构：
[1] Mansoura Univ, Fac Pharm, Dept Pharmacognosy, Mansoura, Egypt
来源：
NATURAL PRODUCT RESEARCH | 2021年 / 35卷 / 15期
关键词：
Dracaena cinnabari; Dragon's blood; chalcone; dihydrochalcone; alpha-glucosidase; CHINESE DRAGONS BLOOD; RED RESIN; FLAVONOIDS; POTENTIALS;
D O I：
10.1080/14786419.2019.1687471
中图分类号：
O69 [应用化学];
学科分类号：
081704 ;
摘要：
A new C-linked chalcone-dihydrochalcone dimer, named dracidione, was isolated from the ethyl acetate extract of dragon's blood resin of Dracaena cinnabari Balf. f. Structure elucidation of the new compound was carried out by means of one- and two-dimensional NMR spectroscopy in addition to high resolution mass spectrometry. The unique structure incorporated a chalcone and a dihydrochalcone, which is reported for the first time from nature. Furthermore, dracidione showed moderate alpha-glucosidase inhibitory activity with IC50= 40.27 mu g/ml.
引用
收藏
页码：2558 / 2563
页数：6
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