Objective To estimate the prevalence and incidence of hypertension and prehypertension and associated factors in adolescent girls. Study design A total of 2368 girls (49% Caucasian, 51% African-American) aged 9 or 10 years enrolled in the National Heart, Lung, and Blood Institute Growth and Health Study had blood pressure, height, and weight measured at annual visits through age 18 to 19 years. Prevalence and incidence of hypertension and prehypertension were calculated. Results On the basis of 2 visits, hypertension prevalence was approximately 1% to 2% in African-American girls and 0.5% in Caucasian girls. Incidence in 8 years was 5.0% and 2.1%, respectively. Obese girls had higher prevalence (approximately 6-fold higher) and incidence (aprroximately 2- to 3-fold higher) compared with girls of normal weight. Similar patterns were found for prehypertension, except that prehypertension occurred more in older girls than younger girls. Dietary factors (lower intake of fiber, potassium, magnesium, and calcium, and higher intake of caffeine and calories) were each associated with hypertension incidence (all P < .05). In multivariate analysis, higher body mass index (P < .001) and lower potassium intake (P = .023) were independently associated with incidence of hypertension. Conclusions Hypertension occurred early in childhood and was related to obesity and other modifiable lifestyle factors. Clinicians should monitor blood pressure during childhood and provide focused diet and physical activity guidance to minimize the development of hypertension. (J Pediatr 2010; 157: 461-7).
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Univ Washington, Seattle, WA 98195 USA
Fred Hutchinson Canc Ctr, Seattle, WA 98109 USAUniv Washington, Seattle, WA 98195 USA
Roxby, Alison C.
Mugo, Nelly R.
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Univ Washington, Seattle, WA 98195 USA
Kenya Govt Med Res Ctr, Nairobi, KenyaUniv Washington, Seattle, WA 98195 USA
Mugo, Nelly R.
Oluoch, Lynda M.
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Kenya Govt Med Res Ctr, Nairobi, KenyaUniv Washington, Seattle, WA 98195 USA
Oluoch, Lynda M.
Tapia, Kenneth
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Univ Washington, Seattle, WA 98195 USAUniv Washington, Seattle, WA 98195 USA
Tapia, Kenneth
Wang, Melody
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Univ Washington, Seattle, WA 98195 USAUniv Washington, Seattle, WA 98195 USA
Wang, Melody
Selke, Stacy
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Univ Washington, Seattle, WA 98195 USAUniv Washington, Seattle, WA 98195 USA
Selke, Stacy
Chohan, Bhavna
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Univ Washington, Seattle, WA 98195 USA
Kenya Govt Med Res Ctr, Nairobi, KenyaUniv Washington, Seattle, WA 98195 USA
Chohan, Bhavna
Micheni, Murugi
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Kenya Govt Med Res Ctr, Nairobi, Kenya
Natl Syndem Dis Control Council, Nairobi, KenyaUniv Washington, Seattle, WA 98195 USA
Micheni, Murugi
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Sycuro, Laura
Yuh, Tiffany
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Univ Washington, Seattle, WA 98195 USAUniv Washington, Seattle, WA 98195 USA
Yuh, Tiffany
Casmir, Edinah
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Kenya Govt Med Res Ctr, Nairobi, KenyaUniv Washington, Seattle, WA 98195 USA
Casmir, Edinah
Kimani, Edith
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Kenya Govt Med Res Ctr, Nairobi, KenyaUniv Washington, Seattle, WA 98195 USA
Kimani, Edith
Maina, Steven Gakuo
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Kenya Govt Med Res Ctr, Nairobi, KenyaUniv Washington, Seattle, WA 98195 USA
Maina, Steven Gakuo
Kiptinness, Catherine
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Kenya Govt Med Res Ctr, Nairobi, KenyaUniv Washington, Seattle, WA 98195 USA
Kiptinness, Catherine
Ngure, Kenneth
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Univ Washington, Seattle, WA 98195 USA
Jomo Kenyatta Univ Agr & Technol, Nairobi, Kenya
Univ Calgary, Calgary, AB, CanadaUniv Washington, Seattle, WA 98195 USA
Ngure, Kenneth
Wald, Anna
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Univ Washington, Seattle, WA 98195 USA
Fred Hutchinson Canc Ctr, Seattle, WA 98109 USAUniv Washington, Seattle, WA 98195 USA