Biotransformation of 2-dimethoxymethyl-5, 6, 7, 8-tetrahydro[1,8]naphthyridine in rat hepatocytes

被引：0
|
作者：
Cui, D [1 ]
Xu, XH [1 ]
Liang, YX [1 ]
Kassahun, K [1 ]
机构：
[1] Merck & Co Inc, Dept Drug Metab, W Point, PA 19486 USA
来源：
DRUG METABOLISM REVIEWS | 2004年 / 36卷
关键词：
D O I：
暂无
中图分类号：
R9 [药学];
学科分类号：
1007 ;
摘要：
405
引用
收藏
页码：202 / 202
页数：1
相关论文
共 50 条
  • [1] Design and synthesis of potent αvβ3 antagonists:: Discovery of 5,6,7,8-tetrahydro[1,8]naphthyridine as a lipophilic, moderately basic guanidine replacement.
    Duggan, ME
    Duong, LT
    Fernandez-Metzler, C
    Fisher, JE
    Gentile, MA
    Gorham, L
    Hartman, GD
    Kimmel, DB
    Leu, CT
    Libby, L
    Lynch, JJ
    Meissner, RS
    Merkle, K
    Nagy, R
    Wallace, T
    Wesolowski, GA
    Zartman, AE
    ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY, 2000, 220 : U566 - U566
  • [2] Synthesis of enantiomerically pure 8-substituted 5,6,7,8-tetrahydro quinolines
    Uenishi, J
    Hamada, M
    SYNTHESIS-STUTTGART, 2002, (05): : 625 - 630
  • [3] Synthesis of enantiomerically pure 8-substituted 5,6,7,8-tetrahydro quinolines
    Uenishi, Junichi
    Hamada, Masahiro
    Synthesis, 2002, (05) : 625 - 630
  • [4] 5-6-7-8-TETRAHYDRO-8-METHYLINDANE-1-5-DIONE
    BOYCE, CBC
    WHITEHURST, JS
    JOURNAL OF THE CHEMICAL SOCIETY, 1959, (JUN): : 2022 - 2024
  • [5] SOME DERIVATIVES OF 1,8-NAPHTHYRIDINE, 1,2-DIHYDROPYRIDO[2,3-B] [1,8]-NAPHTHYRIDINE AND 2H-PYRANO[2,3-B][1,8]NAPHTHYRIDINE
    HENRY, RA
    HAMMOND, PR
    JOURNAL OF HETEROCYCLIC CHEMISTRY, 1977, 14 (06) : 1109 - 1114
  • [6] NEW HETEROCYCLIC DERIVATIVES OF 1'-AMINO-5',6',7',8'-TETRAHYDRO-2'-ACETONAPHTHONE AND 3'-AMINO-5',6',7',8'-TETRAHYDRO-2'-ACETONAPHTHONES
    PRIETO, J
    VEGA, A
    MORAGUES, J
    JOURNAL OF HETEROCYCLIC CHEMISTRY, 1976, 13 (04) : 813 - 819
  • [7] A facile synthesis of the 3-amino-5,6,7,8-tetrahydro[1,6]naphthyridine system and some alkylated and polycyclic homologues
    Harling, JD
    Harrington, FP
    Thompson, M
    SYNTHETIC COMMUNICATIONS, 2001, 31 (05) : 787 - 797
  • [8] SYNTHESIS OF 5,6,7,8-TETRAHYDRO(1)BENZOTHIENO(2.3-D)PYRMIDINES
    ROBBA, M
    TOUZOT, P
    RIQUELME, RM
    COMPTES RENDUS HEBDOMADAIRES DES SEANCES DE L ACADEMIE DES SCIENCES SERIE C, 1973, 276 (01): : 93 - 95
  • [9] SYNTHESIS OF 5-6-7-8-TETRAHYDRO-1-METHYL-BETA-CARBOLINE
    CLEMO, GR
    HOLT, RJW
    JOURNAL OF THE CHEMICAL SOCIETY, 1953, (APR): : 1313 - 1314
  • [10] New heterocyclic systems based on 1-hydrazino-5,6,7,8-tetrahydro[2,7]naphthyridine: 7,8,9,10-tetra-hydro[1,2,4]triazolo[3,4-a]- and 7,8,9,10-tetra-hydro[1,2,4]triazolo[5,1-a][2,7]naphthyridines
    S. N. Sirakanyan
    N. G. Avetisyan
    A. S. Noravyan
    Chemistry of Heterocyclic Compounds, 2012, 48 : 470 - 475
12345