Dual photoredox and cobalt catalysis enpowers site-selective allylic amination

The development of a highly efficient, selective and atom-economical method for the construction of allylic amines are a challenge in green synthetic chemistry. In a recent work published in Nature Catalysis, Lei, Qi, and coworkers reported that the combination of a photoredox catalyst and cobaloxime catalyst enables site-selective allylic amination of various olefins with secondary alkyl amines, affording the valuable tertiary aliphatic allylamines, without the need for external oxidants.