Chiral synthesis of polyketide-derived natural products .51. Stereoselective total synthesis of lysocellin, the representative polyether antibiotic of the lysocellin family .1. Synthesis of C1-C9 and C16-C23 subunits

被引：7

作者：

Horita, K

Inoue, T

Tanaka, K

Yonemitsu, O

机构：

[1] Faculty of Pharmaceutical Sciences, Hokkaido University

[2] Department of Chemistry, Okayama University of Science

来源：

TETRAHEDRON | 1996年 / 52卷 / 02期

关键词：

D O I：

10.1016/0040-4020(95)00905-1

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

The C1-C9 (4) and C16-C23 subunits (9) of lysocellin (1), a representative polyether antibiotic, were synthesized stereoselectively from D-glucose and D-mannitol. Stereocontrolled hydroboration, Michael reaction, Grignard reaction, etc. were successfully applied.

引用

页码：531 / 550

页数：20

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