NORMAL AND RHEUMATOID ARTHRITIS NEUTROPHIL EXTRACELLULAR TRAPS ARE BOTH PRO- AND ANTI-INFLAMMATORY VIA MECHANISMS INVOLVING THE C1Q COMPLEMENT PROTEIN BUT INDEPENDENTLY OF ACPA, LL-37 OR THE INFLAMMASOME

被引:0
|
作者
Ribon, M. [1 ,2 ]
Seninet, S. [1 ,2 ]
Matyja, K. [1 ,2 ]
Sebbag, M. [3 ,4 ]
Clavel, C. [3 ,4 ]
Mussard, J. [1 ,2 ]
Serre, G. [3 ,4 ]
Boissier, M. C. [1 ,2 ,5 ]
Decker, P. [1 ,2 ]
机构
[1] Univ Paris 13, Sorbonne Paris Cite, Paris, France
[2] INSERM, UMR 1125, Li2P, Bobigny, France
[3] Univ Toulouse, Toulouse, France
[4] INSERM, CNRS 1056, UMR 5165, Toulouse, France
[5] Avicenne Hosp, AP HP, Dept Rheumatol, Bobigny, France
关键词
D O I
10.1136/annrheumdis-2016-209124.29
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
A1.29
引用
收藏
页码:A12 / +
页数:2
相关论文
共 5 条
  • [1] Neutrophil extracellular traps from rheumatoid arthritis patients are particularly pro-inflammatory and activate macrophages and neutrophils via mechanisms involving the C1q complement protein but independently of autoantibodies, LL-37, endosomal acidification or the inflammasome
    Ribon, M.
    Seninet, S.
    Matyja, K.
    Sebbag, M.
    Clavel, C.
    Mussard, J.
    Serre, G.
    Boissier, M. C.
    Decker, P.
    EUROPEAN JOURNAL OF CLINICAL INVESTIGATION, 2016, 46 : 90 - 91
  • [2] Neutrophil extracellular traps exert both pro- and anti-inflammatory actions in rheumatoid arthritis that are modulated by Clq and LL-37
    Ribon, Matthieu
    Seninet, Sarra
    Mussard, Julie
    Sebbag, Mireille
    Clavel, Cyril
    Serre, Guy
    Boissier, Marie-Christophe
    Semerano, Luca
    Decker, Patrice
    JOURNAL OF AUTOIMMUNITY, 2019, 98 : 122 - 131
  • [3] NEUTROPHIL EXTRACELLULAR TRAPS ARE NOT ONLY TARGETS FOR ACPA BUT ALSO DIRECTLY TRIGGER PRO- AND ANTI-INFLAMMATORY EFFECTS PARTLY MEDIATED BY THE C1Q COMPLEMENT PROTEIN
    Ribon, M.
    Matyja, K.
    Sebbag, M.
    Clavel, C.
    Mussard, J.
    Serre, G.
    Boissier, M. C.
    Decker, P.
    ANNALS OF THE RHEUMATIC DISEASES, 2015, 74 : A73 - A74
  • [4] Neutrophil Extracellular Traps Are Not Only Targets for ACPA-Positive IgG from Rheumatoid Arthritis Patients but Also Directly Trigger Pro- and Anti-Inflammatory Effects Partly Mediated By the C1q Complement Protein
    Ribon, Matthieu
    Seninet, Sarra
    Matyja, Katarzyna
    Sebbag, Mireille
    Clavel, Cyril
    Mussard, Julie
    Serre, Guy
    Boissier, Marie-Christophe
    Decker, Patrice
    ARTHRITIS & RHEUMATOLOGY, 2015, 67
  • [5] Is the Complement Protein C1q a Pro- or Anti-tumorigenic Factor? Bioinformatics Analysis Involving Human Carcinomas
    Mangogna, Alessandro
    Agostinis, Chiara
    Bonazza, Deborah
    Belmonte, Beatrice
    Zacchi, Paola
    Zito, Gabriella
    Romano, Andrea
    Zanconati, Fabrizio
    Ricci, Giuseppe
    Kishore, Uday
    Bulla, Roberta
    FRONTIERS IN IMMUNOLOGY, 2019, 10