Haematological effects of oral administration of bitopertin, a glycine transport inhibitor, in patients with non-transfusion-dependent β-thalassaemia

被引：15

作者：

Taher, Ali T. ^{[1
]}

Viprakasit, Vip ^{[2
,3
]}

Cappellini, Maria Domenica ^{[4
]}

Kraus, Dominik ^{[5
]}

Cech, Patrick ^{[5
]}

Volz, Dietmar ^{[5
]}

Winter, Erica ^{[6
]}

Nave, Stephane ^{[5
]}

Dukart, Juergen ^{[5
,7
,8
]}

Khwaja, Omar ^{[5
]}

Koerner, Annette ^{[5
]}

Hermosilla, Ricardo ^{[5
]}

Brugnara, Carlo ^{[9
,10
]}

机构：

[1] Amer Univ Beirut, Med Ctr, Dept Internal Med, Div Hematol & Oncol, Beirut, Lebanon

[2] Mahidol Univ, Dept Pediat, Bangkok, Thailand

[3] Mahidol Univ, Div Hematol & Oncol, Siriraj Thalassemia Ctr, Bangkok, Thailand

[4] Univ Milan, Dept Med, CaGranda Fdn IRCCS, Milan, Italy

[5] Roche Innovat Ctr Basel, Roche Pharma Res & Early Dev, Basel, Switzerland

[6] Roche Innovat Ctr, Roche Pharma Res & Early Dev, New York, NY USA

[7] Res Ctr Julich, Inst Neurosci & Med Brain & Behav INM 7, Julich, Germany

[8] Heinrich Heine Univ Dusseldorf, Med Fac, Inst Syst Neurosci, Dusseldorf, Germany

[9] Boston Childrens Hosp, Dept Lab Med, Boston, MA USA

[10] Harvard Med Sch, Dept Pathol, Boston, MA 02115 USA

来源：

BRITISH JOURNAL OF HAEMATOLOGY | 2021年 / 194卷 / 02期

关键词：

bitopertin; haem; iron; reactive oxygen species; beta-thalassemia; ERYTHROPOIESIS;

D O I：

10.1111/bjh.17479

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

引用

页码：474 / 477

页数：4

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