Potential Utility of the Tau Deposit Tracer [18F]T807 (aka [18F]AV-1451) as a PET Biomarker for Neurodegeneration in Clinical Trials

被引:0
|
作者
Mintun, Mark [1 ]
Devous, Michael, Sr. [1 ]
Attardo, Giorgio [1 ]
Joshi, Abhinay [1 ]
Schwarz, Adam [1 ]
Shcherbinin, Sergey [1 ]
Siderowf, Andrew [1 ]
Lin, Yin Guo [1 ]
Liang, Qianwa [1 ]
Conway, Kelly [1 ]
Gomez, Felipe [1 ]
Pontecorvo, Michael [1 ]
机构
[1] Avid Radiopharmaceut, Philadelphia, PA USA
关键词
tau; imaging; PET; neurodegeneration;
D O I
暂无
中图分类号
Q189 [神经科学];
学科分类号
071006 ;
摘要
M145
引用
收藏
页码:S207 / S208
页数:2
相关论文
共 50 条
  • [1] Human Radiation Dosimetry of [18F]AV-1451(T807) to Detect Tau Pathology
    Choi, Jae Yong
    Lyoo, Chul Hyoung
    Lee, Jae Hoon
    Cho, Hanna
    Kim, Kyeong Min
    Kim, Jin Su
    Ryu, Young Hoon
    MOLECULAR IMAGING AND BIOLOGY, 2016, 18 (04) : 479 - 482
  • [2] Human Radiation Dosimetry of [18F]AV-1451(T807) to Detect Tau Pathology
    Jae Yong Choi
    Chul Hyoung Lyoo
    Jae Hoon Lee
    Hanna Cho
    Kyeong Min Kim
    Jin Su Kim
    Young Hoon Ryu
    Molecular Imaging and Biology, 2016, 18 : 479 - 482
  • [3] Synthesis and preliminary evaluations of [18F] AV-1451 ([18F] T807) Analogs as PHF-Tau Protein Imaging Agents
    Huang, Ya-Yao
    Chiu, Ching-Hung
    Tsai, Chia-Ling
    Hsin, Ling-Wei
    Chang, Yu-Ning
    Chou, Shu-Cheng
    Yen, Ruoh-Fang
    Shiue, Chyng-Yann
    JOURNAL OF NUCLEAR MEDICINE, 2017, 58
  • [4] Ongoing development of analysis strategies with [F-18]-T807 (AV-1451): A PET biomarker for tau deposits
    Mintun, Mark
    Joshi, Abhinay
    Shcherbinin, Sergey
    Schwarz, Adam
    Lu, Ming
    Pontecorvo, Michael
    Devous, Michael
    Siderowf, Andrew
    Arora, Anupa
    Skovronsky, Daniel
    JOURNAL OF NUCLEAR MEDICINE, 2014, 55
  • [5] Comparison of New Tau PET-Tracer Candidates With [18F]T808 and [18F]T807
    Declercq, Lieven
    Celen, Sofie
    Lecina, Joan
    Ahamed, Muneer
    Tousseyn, Thomas
    Moechars, Diederik
    Alcazar, Jesus
    Ariza, Manuela
    Fierens, Katleen
    Bottelbergs, Astrid
    Marien, Jonas
    Vandenberghe, Rik
    Andres, Ignacio Jose
    Van Laere, Koen
    Verbruggen, Alfons
    Bormans, Guy
    MOLECULAR IMAGING, 2016, 15 : 1 - 15
  • [6] Fully automated synthesis of a PET AD tau tracer [18F]T807
    Gao, Mingzhang
    Wang, Min
    Zheng, Qi-Huang
    JOURNAL OF NUCLEAR MEDICINE, 2015, 56 (03)
  • [7] Diagnostic utility of regional [18F] AV-1451 tau-PET measurements in PSP
    Whitwell, J.
    Lowe, V.
    Tosakulwong, N.
    Weigand, S.
    Senjem, M.
    Schwarz, C.
    Spychalla, A.
    Petersen, R.
    Jack, C.
    Josephs, K.
    MOVEMENT DISORDERS, 2017, 32
  • [8] [18F]AV-1451 tau-PET and primary progressive aphasia
    Josephs, Keith A.
    Martin, Peter R.
    Botha, Hugo
    Schwarz, Christopher G.
    Duffy, Joseph R.
    Clark, Heather M.
    Machulda, Mary M.
    Graff-Radford, Jonathan
    Weigand, Stephen D.
    Senjem, Matthew L.
    Utianski, Rene L.
    Drubach, Daniel A.
    Boeve, Bradley F.
    Jones, David T.
    Knopman, David S.
    Petersen, Ronald C.
    Jack, Clifford R., Jr.
    Lowe, Val J.
    Whitwell, Jennifer L.
    ANNALS OF NEUROLOGY, 2018, 83 (03) : 599 - 611
  • [9] PET IMAGING OF TAU PATHOLOGY USING [18F]AV-1451 IN CHRONIC TBI
    Okonkwo, David
    Presson, Nora
    Minhas, Davneet
    Laymon, Charles
    Lopresti, Brian
    Mathis, Chet
    Schneider, Walter
    Mountz, James
    JOURNAL OF NEUROTRAUMA, 2016, 33 (13) : A92 - A92
  • [10] Synthesis and quality control of [18F]T807 for tau PET imaging
    Holt, Daniel P.
    Ravert, Hayden T.
    Dannals, Robert F.
    JOURNAL OF LABELLED COMPOUNDS & RADIOPHARMACEUTICALS, 2016, 59 (10): : 411 - 415