QT interval in twins

被引：30

作者：

Carter, N ^{[1
]}

Snieder, H

Jeffery, S

Saumarez, R

Varma, C

Antoniades, L

Spector, TD

机构：

[1] St George Hosp, Sch Med, Dept Med Genet, London SW17 0RE, England

[2] St George Hosp, Sch Med, Dept Cardiol Sci, London SW17 0RE, England

[3] St Thomas Hosp, Twin Res & Genet Epidemiol Unit, London SE1 7EH, England

来源：

JOURNAL OF HUMAN HYPERTENSION | 2000年 / 14卷 / 06期

关键词：

twins; QT; heritability;

D O I：

10.1038/sj.jhh.1001026

中图分类号：

R6 [外科学];

学科分类号：

1002 ; 100210 ;

摘要：

QT interval has been determined in 103 monozygotic (MZ) and 198 dizygotic (DZ) female twins. Mean values of corrected QT (QTc) were almost identical for both groups at 413 ms (MZ) and 412 ms (DZ), There was a significant age and environmental effect on QT interval. Heritability explained about 25% of the variation in QT, Further research will show whether any of the genes known to cause Long QT syndrome have any effect on QT interval at the sub-clinical level.

引用

页码：389 / 390

页数：2

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