Opinion - Coat proteins: shaping membrane transport

被引:304
作者
Bonifacino, JS [1 ]
Lippincott-Schwartz, J [1 ]
机构
[1] NICHHD, Cell Biol & Metab Branch, NIH, Bethesda, MD 20892 USA
关键词
D O I
10.1038/nrm1099
中图分类号
Q2 [细胞生物学];
学科分类号
071009 ; 090102 ;
摘要
Coat proteins allow the selective transfer of macromolecules from one membrane-enclosed compartment to another by concentrating macromolecules into specialized membrane patches and then deforming these patches into small coated vesicles. Recent findings indicate that coat proteins might also participate in the differentiation of membrane domains within organelles and large transport carriers, as well as in the association of the carriers with the cytosketelon and with acceptor organelles.
引用
收藏
页码:409 / 414
页数:6
相关论文
共 53 条
[1]   Assembly of presynaptic active zones from cytoplasmic transport packets [J].
Ahmari, SE ;
Buchanan, J ;
Smith, SJ .
NATURE NEUROSCIENCE, 2000, 3 (05) :445-451
[2]   ER export: public transportation by the COPII coach [J].
Antonny, B ;
Schekman, R .
CURRENT OPINION IN CELL BIOLOGY, 2001, 13 (04) :438-443
[3]   SEQUENTIAL COUPLING BETWEEN COPII AND COPI VESICLE COATS IN ENDOPLASMIC-RETICULUM TO GOLGI TRANSPORT [J].
ARIDOR, M ;
BANNYKH, SI ;
ROWE, T ;
BALCH, WE .
JOURNAL OF CELL BIOLOGY, 1995, 131 (04) :875-893
[4]   COPII - A MEMBRANE COAT FORMED BY SEC PROTEINS THAT DRIVE VESICLE BUDDING FROM THE ENDOPLASMIC-RETICULUM [J].
BARLOWE, C ;
ORCI, L ;
YEUNG, T ;
HOSOBUCHI, M ;
HAMAMOTO, S ;
SALAMA, N ;
REXACH, MF ;
RAVAZZOLA, M ;
AMHERDT, M ;
SCHEKMAN, R .
CELL, 1994, 77 (06) :895-907
[5]   COPI- and COPII-coated vesicles bud directly from the endoplasmic reticulum in yeast [J].
Bednarek, SY ;
Ravazzola, M ;
Hosobuchi, M ;
Amherdt, M ;
Perrelet, A ;
Schekman, R ;
Orci, L .
CELL, 1995, 83 (07) :1183-1196
[6]   Structure of the Sec23/24-Sar1 pre-budding complex of the COPII vesicle coat [J].
Bi, XP ;
Corpina, RA ;
Goldberg, J .
NATURE, 2002, 419 (6904) :271-277
[7]   Adaptins - The final recount [J].
Boehm, M ;
Bonifacino, JS .
MOLECULAR BIOLOGY OF THE CELL, 2001, 12 (10) :2907-2920
[8]  
Boman AL, 2001, J CELL SCI, V114, P3413
[9]   Molecular architecture and functional model of the endocytic AP2 complex [J].
Collins, BM ;
McCoy, AJ ;
Kent, HM ;
Evans, PR ;
Owen, DJ .
CELL, 2002, 109 (04) :523-535
[10]   AP-4, a novel protein complex related to clathrin adaptors [J].
Dell'Angelica, EC ;
Mullins, C ;
Bonifacino, JS .
JOURNAL OF BIOLOGICAL CHEMISTRY, 1999, 274 (11) :7278-7285