Renal clearance of creatinine, urea, para amino hippuric acid, sodium, potassium and chloride during summer and winter seasons in goats

Renal clearance of exogenous inulin and para-amino hippuric acid (PAH) and endogenous creatinine, urea, sodium, potassium and chloride was determined in goats during summer and winter seasons. A highly significant (P<0.01) seasonal difference was recorded in diuresis, blood pH, urine pH, plasma concentration of inulin, creatinine, urea, sodium, potassium, chlorides and renal clearance of inulin, creatinine, urea, sodium, potassium and chlorides. No seasonal difference was observed in plasma concentration and renal clearance of PAH. The glomerular filtration rate in local goats in Pakistan was lower when compared with the literature values from the temperate environments.