Practical Functional and Washing Droplet Routing for Cross-Contamination Avoidance in Digital Microfluidic Biochips

被引:0
|
作者
Wang, Qin [1 ]
Shen, Yiren [1 ]
Yao, Hailong [1 ]
Ho, Tsung-Yi [2 ]
Cai, Yici [1 ]
机构
[1] Tsinghua Univ, Tsinghua Natl Lab Informat Sci & Technol, Dept Comp Sci & Technol, Beijing, Peoples R China
[2] Natl Cheng Kung Univ, Tsinghua Natl Lab Informat Sci & Technol, Tainan, Taiwan
基金
国家教育部博士点专项基金资助; 中国国家自然科学基金;
关键词
Digital microfluidic biochips; Cross-contamination avoidance; Droplet routing; Washing capacity constraint; ALGORITHM;
D O I
暂无
中图分类号
TP [自动化技术、计算机技术];
学科分类号
0812 ;
摘要
In digital microfluidic biochips, cross-contamination of different biomolecule droplets is a major issue. Washing operations are introduced to clean the cross-contamination sites. Existing works have oversimplified assumptions on the washing behavior, which either assume unrealistic infinite washing capacity, or ignore the execution time constraint and/or the routing conflicts between functional and washing droplets. This paper presents the first practical droplet routing flow, which considers realistic issues including the finite washing capacity constraint, and the routing conflicts between washing and functional droplets. Effectiveness of the presented method are validated by real-life biochemical applications.
引用
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页数:6
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