Extensive molecular profiling of squamous cell anal carcinoma in a phase 2 trial population: Translational analyses of the "CARACAS" study

被引:1
|
作者
Prete, Alessandra Anna
Manca, Paolo
Morano, Federica
Rasola, Cosimo
Messina, Marco
Formica, Vincenzo
Corsi, Domenico Cristiano
Cortesi, Enrico
Frassineti, Giovanni Luca
Zampino, M. Giulia
Casagrande, Mariaelena
Masi, Gianluca
Ronzoni, Monica
Scartozzi, Mario
Prisciandaro, Michele
Bergamo, Francesca
Vettore, Valentina
Pietrantonio, Filippo
Fassan, Matteo
Lonardi, Sara
机构
[1] Veneto Inst Oncol IOV IRCCS, Dept Oncol Oncol 1, Padua, Italy
[2] Ist Nazl Tumori, Milan, Italy
[3] Fdn IRCCS Ist Nazl Tumori, Dept Med Oncol, ENETS Ctr Excellence, Milan, Italy
[4] Univ Padua, Unit Surg Oncol & Gastroenterol, Padua, Italy
[5] UOC Oncol Fdn Ist G Giglio, Palermo, Italy
[6] Tor Vergata Univ, Med Oncol Unit, Rome, Italy
[7] Osped San Giovanni Calibita Fatebenefratelli, Med Oncol Unit, Rome, Italy
[8] Sapienza Univ Rome, Rome, Italy
[9] IRCCS, Med Oncol Unit, Ist Sci Romagnolo Studio Cura Tumori IRST, Meldola, Italy
[10] IRCCS, Ist Europeo Oncol, Div Oncol Med Gastrointestinale & Tumori Neurodoc, Milan, Italy
[11] Azienda Sanitaria Univ Integrata Udine, Dept Oncol, Udine, Italy
[12] Azienda Osped Univ Pisana, Pisa, Italy
[13] Ist Sci San Raffaele IRCSS, Dept Oncol, Milan, Italy
[14] Univ Hosp, Med Oncol Unit, Cagliari, Italy
[15] Univ Cagliari, Cagliari, Italy
[16] Fdn IRCCS Ist Nazl Tumori, Dept Med Oncol, Milan, Italy
[17] Fdn IRCCS Ist Nazl Tumori, Dept Med Oncol, Milan, Italy
[18] Univ Hosp Padua, Dept Pathol, Padua, Italy
[19] Veneto Inst Oncol IOV IRCCS, Padua, Italy
关键词
D O I
10.1200/JCO.2022.40.4_suppl.005
中图分类号
R73 [肿瘤学];
学科分类号
100214 ;
摘要
5
引用
收藏
页数:3
相关论文
共 50 条
  • [1] Extensive molecular profiling of squamous cell anal carcinoma in a phase 2 trial population: Translational analyses of the "CARACAS" study
    Prete, Alessandra A.
    Manca, Paolo
    Messina, Marco
    Formica, Vincenzo
    Frassineti, Giovanni L.
    Zampino, Maria G.
    Corsi, Domenico C.
    Orciuolo, Corrado
    Prisciandaro, Michele
    Bergamo, Francesca
    Angerilli, Valentina
    Scartozzi, Mario
    Casagrande, Mariaelena
    Masi, Gianluca
    Ronzoni, Monica
    Morano, Federica
    Vettore, Valentina
    Salmaso, Roberta
    Rasola, Cosimo
    Maddalena, Giulia
    del Bianco, Paola
    Milione, Massimo
    Cremolini, Chiara
    Fassan, Matteo
    Pietrantonio, Filippo
    Lonardi, Sara
    EUROPEAN JOURNAL OF CANCER, 2023, 182 : 87 - 97
  • [2] Randomized phase II trial of avelumab alone or in combination with cetuximab for patients with previously treated, locally advanced, or metastatic squamous cell anal carcinoma: the CARACAS study
    Lonardi, Sara
    Prete, Alessandra Anna
    Morano, Federica
    Messina, Marco
    Formica, Vincenzo
    Corsi, Domenico Cristiano
    Orciuolo, Corrado
    Frassineti, Giovanni Luca
    Zampino, Maria Giulia
    Casagrande, Mariaelena
    Masi, Gianluca
    Ronzoni, Monica
    Scartozzi, Mario
    Buonadonna, Angela
    Mosconi, Stefania
    Ratti, Margherita
    Sartore-Bianchi, Andrea
    Tamburini, Emiliano
    Prisciandaro, Michele
    Bergamo, Francesca
    Spada, Massimiliano
    Corallo, Salvatore
    Vettore, Valentina
    Loupakis, Fotios
    Fassan, Matteo
    Del Bianco, Paola
    Zagonel, Vittorina
    Pietrantonio, Filippo
    JOURNAL FOR IMMUNOTHERAPY OF CANCER, 2021, 9 (11)
  • [3] Randomized phase II trial of avelumab alone or with cetuximab for unresectable, locally advanced or metastatic squamous cell anal carcinoma progressed to at least one line of treatment: The CARACAS study.
    Lonardi, Sara
    Pietrantonio, Filippo
    Prete, Alessandra Anna
    Messina, Marco
    Renzi, Nicola
    Corsi, Domenico C.
    Urbano, Federica
    Frassineti, Giovanni Luca
    Zampino, M. Giulia
    Ronzoni, Monica
    Scartozzi, Mario
    Casagrande, Mariaelena
    Boccaccino, Alessandra
    Bergamo, Francesca
    Prisciandaro, Michele
    Rasola, Cosimo
    Corallo, Salvatore
    Del Bianco, Paola
    Vettore, Valentina
    Zagonel, Vittorina
    JOURNAL OF CLINICAL ONCOLOGY, 2020, 38 (15)
  • [4] Final results of the CARACAS study: Randomized phase II trial of avelumab alone or with cetuximab for unresectable, locally advanced or metastatic squamous cell anal carcinoma progressed to at least one line of treatment
    Lonardi, S.
    Pietrantonio, F.
    Prete, A. A.
    Messina, M.
    Formica, V.
    Corsi, D. C.
    Cortesi, E.
    Frassineti, L. G.
    Zampino, M. G.
    Ronzoni, M.
    Scartozzi, M.
    Casagrande, M.
    Conca, V.
    Bergamo, F.
    Prisciandaro, M.
    Intini, R.
    Antista, M.
    Paola, D. B.
    Vettore, V.
    Zagonel, V.
    ANNALS OF ONCOLOGY, 2020, 31 : S412 - S412
  • [5] RADIANCE - Radiochemotherapy with or without Durvalumab in the treatment of anal squamous cell carcinoma: A randomized multicenter phase II trial
    Martin, Daniel
    Balermpas, Panagiotis
    Gollrad, Johannes
    Weiss, Christian
    Valentini, Chiara
    Stuschke, Martin
    Schaefer, Henning
    Henkenberens, Christoph
    Debus, Juergen
    Krug, David
    Kuhnt, Thomas
    Brunner, Thomas
    Bostel, Tilman
    Engenhart-Cabillic, Rita
    Nestle, Ursula
    Combs, Stephanie E.
    Belka, Claus
    Hautmann, Matthias
    Hildebrandt, Guido
    Gani, Cihan
    Polat, Buelent
    Roedel, Claus
    Fokas, Emmanouil
    CLINICAL AND TRANSLATIONAL RADIATION ONCOLOGY, 2020, 23 : 43 - 49
  • [6] Combination immunotherapy of squamous cell carcinoma of the head and neck - A phase 2 trial
    Barrera, JL
    Verastegui, E
    Meneses, A
    Zinser, J
    de la Garza, J
    Hadden, JW
    ARCHIVES OF OTOLARYNGOLOGY-HEAD & NECK SURGERY, 2000, 126 (03) : 345 - 351
  • [7] Molecular screening and early phase trial inclusion for head and neck squamous cell carcinoma patients
    Vozy, A.
    Roussel-Simonin, C.
    Houessinon, A.
    Bayle, A.
    Blanc-Durand, F.
    Ferrand, F. R.
    Fouilloux, A.
    Iacob, M.
    Khalife, N.
    Ponce, S.
    Loriot, Y.
    Baldini, C.
    Italiano, A.
    Even, C.
    ANNALS OF ONCOLOGY, 2022, 33 (08) : S1423 - S1424
  • [8] A phase II study of concurrent chemoradiotherapy with 5-fluorouracil and mitomycin-C for squamous cell carcinoma of the anal canal (the JROSG 10-2 trial)
    Murofushi, Keiko Nemoto
    Itasaka, Satoshi
    Shimokawa, Mototsugu
    Murakami, Yuji
    Yamamoto, Takaya
    Nishimura, Yasumasa
    Kudo, Shigehiro
    Sakamoto, Takashi
    Ariga, Takuro
    Ogo, Etsuyo
    Taguchi, Kentaro
    Jingu, Keiichi
    Ogawa, Kazuhiko
    JOURNAL OF RADIATION RESEARCH, 2023, 64 (01) : 154 - 161
  • [9] Trends of incidence and survival in squamous-cell carcinoma of the anal canal in France: a population-based study
    Bouvier, Anne-Marie
    Belot, Aurelien
    Manfredi, Sylvain
    Jooste, Valerie
    Uhry, Zoe
    Faivre, Jean
    Duport, Nicolas
    Grabar, Sophie
    EUROPEAN JOURNAL OF CANCER PREVENTION, 2016, 25 (03) : 182 - 187
  • [10] PHASE 2 TRIAL OF PIPERAZINEDIONE IN TREATMENT OF ADVANCED SQUAMOUS-CELL CARCINOMA OF CERVIX
    THIGPEN, JT
    HOMESLEY, H
    PREM, K
    MLADINEO, J
    PROCEEDINGS OF THE AMERICAN ASSOCIATION FOR CANCER RESEARCH, 1978, 19 (MAR): : 162 - 162