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Advancing precision medicine in healthcare: addressing implementation challenges to increase pharmacogenetic testing in the clinical setting
被引:7
|作者:
Dong, Olivia M.
Wiltshire, Tim
机构:
[1] Univ North Carolina Chapel Hill, Div Pharmacotherapy & Expt Therapeut, UNC Eshelman Sch Pharm, Chapel Hill, NC USA
[2] Univ North Carolina Chapel Hill, Ctr Pharmacogen & Individualized Therapy, Chapel Hill, NC USA
关键词:
precision medicine;
pharmacogenetics;
preemptive genotyping;
CONSORTIUM CPIC GUIDELINES;
UNIVERSITY-OF-FLORIDA;
PERSONALIZED MEDICINE;
2014;
UPDATE;
PATIENTS PROJECT;
GENOTYPE;
PROGRAM;
DESIGN;
THERAPY;
TIME;
D O I:
10.1152/physiolgenomics.00029.2017
中图分类号:
Q2 [细胞生物学];
学科分类号:
071009 ;
090102 ;
摘要:
The incorporation of precision medicine into the clinical setting is becoming increasingly feasible with the availability of more affordable genetic sequencing technologies and successful genetic associations with phenotypes, especially in the pharmacogenomic field. Although substantial progress has been made to ensure successful uptake of pharmacogenomic testing in the clinical setting already, many challenges still remain for sustainable implementation. The importance of pharmacogenomic information in patient care, identifying key barriers, and proposed solutions for advancing pharmacogenomic implementation will be discussed.
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页码:346 / 354
页数:9
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