ent-Pimarane type diterpenes from Gnaphalium gaudichaudianum

被引:38
|
作者
Meragelman, TL
Silva, GL
Mongelli, E
Gil, RR
机构
[1] Univ Nacl Cordoba, CONICET, IMBIV, Fac Ciencias Quim,Dept Quim Organ, RA-5000 Cordoba, Argentina
[2] Univ Buenos Aires, CONICET, IQUIMEFA, Catedra Microbiol Ind & Tecnol, Buenos Aires, DF, Argentina
关键词
Gnaphalium gaudichaudianum; asteraceae; diterpenes; ent-pimar-15-ene-3; alpha; 8; alpha-diol; Artemia salina toxicity test;
D O I
10.1016/S0031-9422(02)00611-8
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
Fractionation of the methanol extract of Gnaphalium gaudichaudianum DC afforded one new and six known ent-pimarane diterpenes together with velutin, squalene and stigmasterol. The structure of the new compound was established on the basis of extensive I D and 2D NMR spectroscopic data interpretation. Two of the isolated compounds exhibited moderate toxicity in the Artemia salina toxicity test. (C) 2002 Elsevier Science Ltd. All rights reserved.
引用
收藏
页码:569 / 572
页数:4
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