Obesity is associated with an increased prevalence of penicillin allergy

To the best of our knowledge, this is the first study to investigate the association of air pollution markers with nasal microbiota, adjusting for multiple socioeconomic factors at the block group level for each individual. Adjusting for asthma and atopy did not affect these results. The data collected were obtained from reputable governmental sources rather than relying on self-reported data, which is subject to numerous biases. The middle meatus was selected as a representation of the sinonasal cavity because the microbiota of the anterior nares is labile. We used the V4 16S rRNA region for analysis, as mentioned by the Earth Microbiome Project; however, we acknowledge that V2-V3 16S rRNA regions are often used for resolution of low-rank taxa. In addition, we did not have sinus tissue from healthy controls, thus limiting the ability to compare PM2.5-related associations in CRS vs healthy patient tissue. In conclusion, we found that a decreased relative abun