Synthesis and Biological Activities of 6-Hydroxyaurone Derivatives

被引：7
|
作者：
Bao, Yong-Tuan [1 ]
Zhang, Min [1 ]
Li, Ting [1 ]
Xiao, Hui-Feng [1 ]
Zhao, Ting [1 ]
Xu, Xiao-Hua [2 ]
Yang, Liu-Qing [1 ]
机构：
[1] Jiangsu Univ, Sch Chem & Chem Engn, Zhenjiang 212013, Jiangsu, Peoples R China
[2] Nankai Univ, Res Inst Elementoorgan Chem, State Key Lab Elementoorgan Chem, Tianjin 300071, Peoples R China
来源：
JOURNAL OF HETEROCYCLIC CHEMISTRY | 2016年 / 53卷 / 02期
关键词：
LONCHOCARPUS-CASTILLOI; AURONES; METABOLITE;
D O I：
10.1002/jhet.2497
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
A series of 6-hydroxyaurone derivatives were synthesized in satisfactory yields and characterized by IR, H-1 NMR, C-13 NMR, and HRMS or elemental analysis. The structure of compound 3e was further confirmed by X-ray crystal analysis. Bioassay results indicated that some of the target compounds displayed moderate herbicidal activity against the dicotyledonous plant Brassica campestris L. at 100 mu gmL(-1), and some compounds also showed significant antiproliferative activity against tumor cell lines Hela, HepG-2, and MCF-7.
引用
收藏
页码：637 / 642
页数：6
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