Sleep Apnea Research in Animals Past, Present, and Future

被引：51

作者：

Chopra, Swati ^{[1
]}

Polotsky, Vsevolod Y. ^{[1
]}

Jun, Jonathan C. ^{[1
]}

机构：

[1] Johns Hopkins Univ, Sch Med, Dept Med, Div Pulm & Crit Care Med, 5501 Hopkins Bayview Circle,Room 4A30A, Baltimore, MD 21224 USA

来源：

AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY | 2016年 / 54卷 / 03期

关键词：

sleep apnea; animal; intermittent hypoxia; fragmentation; CHRONIC INTERMITTENT HYPOXIA; BLOOD-PRESSURE; OPTOGENETIC CONTROL; AIRWAY-OBSTRUCTION; MOUSE MODEL; RAT MODEL; FRAGMENTATION; RESPONSES; INFLAMMATION; AROUSAL;

D O I：

10.1165/rcmb.2015-0218TR

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

Obstructive sleep apnea (OSA) is a common disorder that describes recurrent collapse of theupper airway during sleep. Animal models have been pivotal to the understanding of OSA pathogenesis, consequences, and treatment. In this review, we highlight the history of OSA research in animals and include the discovery of animals with spontaneous OSA, the induction of OSA in animals, and the emulation of OSA using exposures to intermittent hypoxia and sleep fragmentation.

引用

页码：299 / 305

页数：7

共 50 条

[1] Sleep apnea - Past, present, future
Grunstein, Ronald R.
Phillips, Craig L.
Liu, Peter Y.
SLEEP MEDICINE REVIEWS, 2008, 12 (01) : 1 - 4
[2] Transoral Robotic Surgery for Obstructive Sleep Apnea: Past, Present, and Future
Vicini, Claudio
Montevecchi, Filippo
SLEEP MEDICINE CLINICS, 2019, 14 (01) : 67 - +
[3] Upper Airway Stimulation for Obstructive Sleep Apnea: Past, Present, and Future
Dedhia, Raj C.
Strollo, Patrick J., Jr.
Soose, Ryan J.
SLEEP, 2015, 38 (06) : 899 - 906
[4] The European Sleep Research Society - past, present and future
Deboer, Tom
Arnardottir, Erna Sif
Landolt, Hans-Peter
Luppi, Pierre Herve
McNicholas, Walter T.
Pevernagie, Dirk
Plazzi, Giuseppe
JOURNAL OF SLEEP RESEARCH, 2022, 31 (04)
[5] SLEEP:: Past, present and future
Roth, T
SLEEP, 2002, 25 (01) : 4A - 4A
[6] Sleep: Past, present & future
Roth, T
SLEEP, 2002, 25 (03) : 267 - 267
[7] Diagnosing Sleep Apnea-Hypopnea Syndrome in Children: Past, Present, and Future
Brockmann, Pablo E.
Luz Alonso-Alvarez, Maria
Gozal, David
ARCHIVOS DE BRONCONEUMOLOGIA, 2018, 54 (06): : 303 - 305
[8] Relationship between obstructive sleep apnea and pulmonary hypertension: past, present and future
Lenka, Jyotirmayee
Foley, Raymond
Metersky, Mark
Salmon, Adrian
EXPERT REVIEW OF RESPIRATORY MEDICINE, 2024, 18 (3-4) : 85 - 97
[9] Past, present, and future of sleep medicine research in Latin America
Pedemonte, Marisa
Brockmann, Pablo E.
DelRosso, Lourdes M.
Andersen, Monica L.
JOURNAL OF CLINICAL SLEEP MEDICINE, 2021, 17 (05): : 1133 - 1139
[10] Transgenic animals: past, present and future
Felmer, R
ARCHIVOS DE MEDICINA VETERINARIA, 2004, 36 (02) : 105 - 117

← 1 2 3 4 5 →