Expansion and fixation properties of a new braided biodegradable urethral stent:: An experimental study in the rabbit

被引:24
|
作者
Vaajanen, A [1 ]
Nuutinen, JP
Isotalo, T
Törmälä, P
Tammela, TLJ
Talja, M
机构
[1] Tampere Univ Hosp, Dept Urol, Tampere, Finland
[2] Univ Tampere, Sch Med, FIN-33101 Tampere, Finland
[3] Tampere Univ Technol, Inst Biomat, FIN-33101 Tampere, Finland
[4] Paijat Hame Cent Hosp, Dept Surg, Lahti, Finland
来源
JOURNAL OF UROLOGY | 2003年 / 169卷 / 03期
关键词
urethra; stents; rabbits; polymers; urethral stricture;
D O I
10.1097/01.ju.0000049229.12451.13
中图分类号
R5 [内科学]; R69 [泌尿科学(泌尿生殖系疾病)];
学科分类号
1002 ; 100201 ;
摘要
Purpose: Biodegradable spiral urethral stents have been used with favorable results combined with thermal treatments of the prostate and for recurrent urethral strictures but the configuration of the helical spiral is not ideal. We developed a new tubular mesh configuration for the biodegradable urethral stent and evaluated its expansion and locking properties in the rabbit urethra. Materials and Methods: The stents were made of self-reinforced polylactic acid polymer (Bionx Implants, Ltd., Tampere, Finland) blended with BaSO4 (Alfa Chem, New York, New York) to achieve radiopacity. Two braiding patterns, that is I over 1 and 2 over 2 + 1, were used to produce a tubular mesh structure. Stainless steel stents (pattern I over 1) served as controls. The stents were inserted into the posterior urethra of 27 male rabbits. The animals were sacrified after 1 week, 1 and 6 months, respectively. X-rays were done immediately after stent insertion and at sacrifice. Longitudinal movement and expansion were assessed on the x-rays. Results: All stents maintained position in the urethra without fixation. Macroscopic disorientation of the structure of the 2 over 2 + 1 braided self-reinforced polylactic acid polymer stents began before 1 month, while 1 over 1 braided stents retained their construction. At 6 months 3 of 6 biodegradable stents were degraded. Average longitudinal movement was 2 mm. (range 1 to 3) in the 1 over 1 self-reinforced polylactic acid polymer group, 2 mm. (range 0 to 7) in the 2 over 2 + 1 polylactic acid group and 3 mm. (range 3 to 3) in controls at 1 month. Conclusions: Biodegradable polymers are suitable materials for braided urethral stents. The expansion properties of the 2 braiding models tested in this study sufficed to fix the stents in situ in the prostatic urethra. However, the 1 over 1 braiding pattern was superior to the 2 over 2 + 1 pattern, in that it retained its macroscopic construction until the degradation of single self-reinforced polylactic acid polymer fibers.
引用
收藏
页码:1171 / 1174
页数:4
相关论文
共 50 条
  • [41] Experimental Assessment of New Generation of Ureteral Stents: Biodegradable and Antireflux Properties
    Soria, Federico
    de la Cruz, Julia E.
    Budia, Alberto
    Serrano, Alvaro
    Galan-Llopis, Juan Antonio
    Sanchez-Margallo, Francisco M.
    JOURNAL OF ENDOUROLOGY, 2020, 34 (03) : 359 - 365
  • [42] Biodegradable PTX-PLGA-coated magnesium stent for benign esophageal stricture: An experimental study
    Liu, Lin-Lin
    Qin, Juan
    Zeng, Chu-Hui
    Du, Rui-Jie
    Pan, Tao
    Ji, Jia-Jie
    Lu, Li-Gong
    Chen, Lei
    Liu, Dong-Fang
    Yang, Jian
    He, Shi-Cheng
    Zhu, Hai-Dong
    Teng, Gao-Jun
    ACTA BIOMATERIALIA, 2022, 146 : 495 - 505
  • [43] Annuloplasty for valve repair with a new biodegradable ring: An experimental study
    Kalangos, Afksendiyos
    Sierra, Jorge
    Vala, Dominique
    Cikirikcioglu, Mustafa
    Walpoth, Beat
    Orrit, Xavier
    Pomar, Jos
    Mestres, Carlos
    Albanese, Sonia
    Jhurry, Dhanjay
    JOURNAL OF HEART VALVE DISEASE, 2006, 15 (06): : 783 - 790
  • [44] Experimental study on thermal expansion properties of GMZ bentonite
    Cao S.-F.
    Liu Y.-M.
    Xie J.-L.
    Yan A.
    Gao Y.-F.
    Tong Q.
    Yantu Gongcheng Xuebao/Chinese Journal of Geotechnical Engineering, 2022, 44 (02): : 377 - 383
  • [45] Experimental study of a new-generation stent: Multilayer stent for aneurysm and restenosis treatment
    Lobato, A. C.
    JOURNAL OF ENDOVASCULAR THERAPY, 2007, 14 : I16 - I17
  • [46] URETHRAL RECONSTRUCTION WITH A NEW SYNTHETIC ABSORBABLE DEVICE - AN EXPERIMENTAL-STUDY
    OLSEN, L
    BOWALD, S
    BUSCH, C
    CARLSTEN, J
    ERIKSSON, I
    SCANDINAVIAN JOURNAL OF UROLOGY AND NEPHROLOGY, 1992, 26 (04): : 323 - 326
  • [47] Comparison of two types of fixation for proximal tibial epiphysiodesis: An experimental study in a rabbit model
    Bayrak, Alkan
    Duramaz, Altug
    Kizilkaya, Cemal
    Celik, Malik
    Kural, Cemal
    Altinay, Serdar
    Kural, Alev
    Basaran, Serdar Hakan
    JOINT DISEASES AND RELATED SURGERY, 2021, 32 (02): : 468 - 477
  • [48] Study on the thermal expansion properties of viscoelastic resin-based 3D braided composites
    Sun, H. (hysun@nuaa.edu.cn), 1600, Huazhong University of Science and Technology (33):
  • [49] New bioabsorbable tracheal stent - comparison of tissue reaction in experimental rabbit model; poly-L-lactide and silicone stent
    Saito, Y
    Minami, K
    Nakao, Y
    Kobayashi, M
    Omiya, H
    Imamura, H
    Okamura, A
    BRONCHOLOGY AND BRONCHOESOPHAGOLOGY: STATE OF THE ART, 2001, 1217 : 846 - 848
  • [50] The experimental study of a new kind absorbable magnesium alloy stent
    Shuixiang, Y.
    Wang, L. L.
    Cui, Y. X.
    Wang, E. D.
    Yang, J. P.
    Zhu, J. W.
    Wang, P.
    Lei, L. C.
    EUROPEAN HEART JOURNAL, 2012, 33 : 752 - 752