Highly Efficient, ZFN-Driven Knockout of Surface Expression of the T-Cell Receptor and HLA Class I Proteins in Human T-Cells for Enhancing Allogeneic Adoptive Cell Therapies

被引：1

作者：

Lee, Gary K. ^{[1
]}

Liu, Pei-qi ^{[1
]}

Gandhi, Nimisha ^{[1
]}

Truong, Lynn ^{[1
]}

Reik, Andreas ^{[1
]}

Lam, Stephen ^{[1
]}

Hinkley, Sarah J. ^{[1
]}

Miller, Jeffrey C. ^{[1
]}

Paschon, David E. ^{[1
]}

Zhang, Lei ^{[1
]}

Rebar, Edward J. ^{[1
]}

Holmes, Michael C. ^{[1
]}

机构：

[1] Sangamo BioSci, Richmond, CA USA

来源：

MOLECULAR THERAPY | 2016年 / 24卷

关键词：

D O I：

10.1016/S1525-0016(16)33449-9

中图分类号：

Q81 [生物工程学（生物技术）]; Q93 [微生物学];

学科分类号：

071005 ; 0836 ; 090102 ; 100705 ;

摘要：

641

引用

页码：S254 / S254

页数：1

共 50 条

[1] Genetic Ablation of HLA Class I, Class II, and the T-cell Receptor Enables Allogeneic T Cells to Be Used for Adoptive T-cell Therapy
Kagoya, Yuki
Guo, Tingxi
Yeung, Brian
Saso, Kayoko
Anczurowski, Mark
Wang, Chung-Hsi
Murata, Kenji
Sugata, Kenji
Saijo, Hiroshi
Matsunaga, Yukiko
Ohashi, Yota
Butler, Marcus O.
Hirano, Naoto
CANCER IMMUNOLOGY RESEARCH, 2020, 8 (07) : 926 - 936
[2] Lifespan of human memory T-cells in the absence of T-cell receptor expression
Umeki, S
Kusunoki, Y
Cologne, JB
Iwamoto, KS
Hirai, Y
Seyama, T
Ohama, K
Kyoizumi, S
IMMUNOLOGY LETTERS, 1998, 62 (02) : 99 - 104
[3] HLA class-I-specific inhibitory receptor in human T lymphocytes: Interference with T-cell functions
Mingari, MC
Ponte, M
Vitale, C
Schiavetti, F
Bellomo, R
Bertone, S
Nanni, L
RESEARCH IN IMMUNOLOGY, 1997, 148 (03): : 150 - 155
[4] EXPRESSION OF THE T-CELL RECEPTOR GAMMA-CHAIN GENE-PRODUCTS ON THE SURFACE OF PERIPHERAL T-CELLS AND T-CELL BLASTS GENERATED BY ALLOGENEIC MIXED LYMPHOCYTE-REACTION
MAEDA, K
NAKANISHI, N
ROGERS, BL
HASER, WG
SHITARA, K
YOSHIDA, H
TAKAGAKI, Y
AUGUSTIN, AA
TONEGAWA, S
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1987, 84 (18) : 6536 - 6540
[5] EXPRESSION OF 2 T-CELL RECEPTOR-ALPHA CHAINS ON THE SURFACE OF NORMAL MURINE T-CELLS
HEATH, WR
CARBONE, FR
BERTOLINO, P
KELLY, J
COSE, S
MILLER, JFAP
EUROPEAN JOURNAL OF IMMUNOLOGY, 1995, 25 (06) : 1617 - 1623
[6] EXPRESSION OF 2 ALPHA-CHAINS ON THE SURFACE OF T-CELLS IN T-CELL RECEPTOR TRANSGENIC MICE
HEATH, WR
MILLER, JFAP
JOURNAL OF EXPERIMENTAL MEDICINE, 1993, 178 (05): : 1807 - 1811
[7] POLYCLONAL USE OF T-CELL RECEPTOR-ALPHA FOR HUMAN T-CELL LYMPHOTROPIC VIRUS TYPE I-INFECTED T-CELLS
MASUOKA, K
SAGAWA, K
MOCHIZUKI, M
OIZUMI, K
ITOH, K
INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE, 1995, 36 (01) : 254 - 258
[8] HUMAN T-CELL RECEPTOR TCRAV, TCRBV, AND TCRAJ SEQUENCES NEWLY FOUND IN T-CELL CLONES REACTIVE WITH ALLOGENEIC HLA CLASS-II ANTIGENS
OBATA, F
TSUNODA, M
KANEKO, T
ITO, K
ITO, I
MASEWICZ, S
MICKELSON, EM
OLLIER, WER
PAWELEC, G
CELLA, M
FERRARA, GB
KASHIWAGI, N
IMMUNOGENETICS, 1993, 38 (01) : 67 - 70
[9] Absent or low expression of T-cell receptor ζ-chain in T-cells infiltrating human pathological skin conditions
Alaibac, M
Pigozzi, B
Saponeri, A
Belloni-Fortina, A
Peserico, A
JOURNAL OF INVESTIGATIVE DERMATOLOGY, 2002, 119 (03) : 735 - 735
[10] PROGRAMMED CELL-DEATH OF T-CELLS SIGNALED BY THE T-CELL RECEPTOR AND THE ALPHA-3 DOMAIN OF CLASS-I MHC
SAMBHARA, SR
MILLER, RG
SCIENCE, 1991, 252 (5011) : 1424 - 1427

← 1 2 3 4 5 →