Direct microwave synthesis of N,N′-diacylhydrazines and boc-protected hydrazides by in situ carbonylations under air

被引：33

作者：

Herrero, MA ^{[1
]}

Wannberg, J ^{[1
]}

Larhed, M ^{[1
]}

机构：

[1] Univ Uppsala, Dept Med Chem, S-75123 Uppsala, Sweden

来源：

SYNLETT | 2004年 / 13期

关键词：

microwave; carbonylation; molybdenum hexacarbonyl; hydrazide; fluorous;

D O I：

10.1055/s-2004-832837

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Palladium-catalyzed hydrazidocarbonylations of aryl iodides and bromides were performed by controlled microwave irradiation, employing Mo(CO)(6) as a convenient CO source. A fluorous phosphine ligand was succesfully used to recycle the catalytic system. Finally, dehydration of a diacylhydrazine to the corresponding 1,3,4-oxadiazole was achieved with POCl3 in a one-pot procedure.

引用

页码：2335 / 2338

页数：4

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