There are numerous percolation studies of unconventional reservoirs showing that in tight or low-permeability formations, the oil flow behavior could be described by the Pre-Darcy mechanism. However, for the CO2 Huff-nPuff operations, the most presented low-velocity Pre-Darcy flow models may result in an erroneous evaluation due to the intensive boundary layer thickness changes caused by the CO2 extraction and dissolution. In this paper, with multiple parameters fitting the seepage experimental results of the studied area, a unified dimensional Pre-Darcy flow model for CO2 enhanced oil recovery (EOR) is derived from the classic Poiseuille model. Then, the proposed flow model is applied in the compositional simulator for analyzing the viscosity-dependent boundary layer (VDBL) effect, applicability evaluation in Huff-Puff EOR, and field history matching. The results indicate that the VDBL effect improves the oil mobility in injection periods and lowers the residual oil saturation at the front of the CO2 convection-diffusion area in reproduction periods. Additionally, the nonlinear parameter alpha and the shape parameter beta enhance the proposed model's applicability for the Huff process and the Puff process respectively. Finally, by adjusting the parameters alpha and beta for different permeability intervals of the geological model, the flow model is successfully applied in the oil production matching of the Y6 well, which exhibits its reliability in the history matching.