Proteasomes: Machines for all reasons

被引：187
|
作者：
DeMartino, George N. [1 ]
Gillette, Thomas G. [1 ]
机构：
[1] Univ Texas, SW Med Ctr, Dept Physiol, Dallas, TX 75390 USA
来源：
CELL | 2007年 / 129卷 / 04期
关键词：
D O I：
10.1016/j.cell.2007.05.007
中图分类号：
Q5 [生物化学]; Q7 [分子生物学];
学科分类号：
071010 ; 081704 ;
摘要：
Emerging data reveal that besides degrading proteins tagged with ubiquitin, the proteasome plays a more varied and decisive role in cellular regulation than previously imagined. In this issue, Hanna et al. (2007) expand our view of the proteasome by showing that under certain conditions, proteasome composition can be altered to control ubiquitin homeostasis.
引用
收藏
页码：659 / 662
页数：4
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