Background and Purpose - This study aimed to independently derive an intracerebral hemorrhage grading scale ( ICH-GS) for prediction of 3 outcome measures. Methods - We evaluated 378 patients with primary ICH at hospital arrival and during the next 30 days. Independent predictors were identified by multivariate models of in-hospital and 30-day mortality. Points were allotted to each predictor based on its prognostic performance. ICH-GS was also evaluated to predict good 30-day functional status and ICH-GS was compared with the ICH score as the reference scoring system. Results - Independent predictors were age, Glasgow Coma Scale, ICH location, ICH volume, and intraventricular extension, all components of the ICH score. Nevertheless, different cutoffs and scoring improved substantially the prognostic power of the predictors. Compared with the ICH score, ICH-GS explained more variance in the 3 outcome measures, had higher sensitivity in predicting in-hospital and 30-day mortality, and performed equally well in predicting good functional outcome at 30 days follow up. Conclusions - The derived ICH-GS is a simple yet robust scale in predicting in-hospital and 30-day mortality, as well as good 30-day functional status, with equivalent performance.
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Univ Buenos Aires, Hosp JM Ramos Mejia, Dept Neurol, Stroke Serv, RA-1425 Buenos Aires, DF, ArgentinaUniv Buenos Aires, Hosp JM Ramos Mejia, Dept Neurol, Stroke Serv, RA-1425 Buenos Aires, DF, Argentina
Mauriño, J
Saposnik, G
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Univ Buenos Aires, Hosp JM Ramos Mejia, Dept Neurol, Stroke Serv, RA-1425 Buenos Aires, DF, ArgentinaUniv Buenos Aires, Hosp JM Ramos Mejia, Dept Neurol, Stroke Serv, RA-1425 Buenos Aires, DF, Argentina
Saposnik, G
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Lepera, S
Rey, RC
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Univ Buenos Aires, Hosp JM Ramos Mejia, Dept Neurol, Stroke Serv, RA-1425 Buenos Aires, DF, ArgentinaUniv Buenos Aires, Hosp JM Ramos Mejia, Dept Neurol, Stroke Serv, RA-1425 Buenos Aires, DF, Argentina
Rey, RC
Sica, RE
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Univ Buenos Aires, Hosp JM Ramos Mejia, Dept Neurol, Stroke Serv, RA-1425 Buenos Aires, DF, ArgentinaUniv Buenos Aires, Hosp JM Ramos Mejia, Dept Neurol, Stroke Serv, RA-1425 Buenos Aires, DF, Argentina
机构:
Massachusetts Gen Hosp, Hemorrhag Stroke Res Program, Boston, MA 02114 USA
Massachusetts Gen Hosp, Ctr Human Genet Res, Boston, MA 02114 USAMassachusetts Gen Hosp, Hemorrhag Stroke Res Program, Boston, MA 02114 USA
Rost, Natalia S.
Smith, Eric E.
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Massachusetts Gen Hosp, Hemorrhag Stroke Res Program, Boston, MA 02114 USAMassachusetts Gen Hosp, Hemorrhag Stroke Res Program, Boston, MA 02114 USA
Smith, Eric E.
Chang, Yuchiao
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Massachusetts Gen Hosp, Dept Med, Boston, MA 02114 USAMassachusetts Gen Hosp, Hemorrhag Stroke Res Program, Boston, MA 02114 USA
Chang, Yuchiao
Snider, Ryan W.
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Massachusetts Gen Hosp, Hemorrhag Stroke Res Program, Boston, MA 02114 USAMassachusetts Gen Hosp, Hemorrhag Stroke Res Program, Boston, MA 02114 USA
Snider, Ryan W.
Chanderraj, Rishi
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Massachusetts Gen Hosp, Hemorrhag Stroke Res Program, Boston, MA 02114 USA
Massachusetts Gen Hosp, Ctr Human Genet Res, Boston, MA 02114 USAMassachusetts Gen Hosp, Hemorrhag Stroke Res Program, Boston, MA 02114 USA
Chanderraj, Rishi
Schwab, Kristin
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Massachusetts Gen Hosp, Hemorrhag Stroke Res Program, Boston, MA 02114 USAMassachusetts Gen Hosp, Hemorrhag Stroke Res Program, Boston, MA 02114 USA
Schwab, Kristin
FitzMaurice, Emily
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Massachusetts Gen Hosp, Hemorrhag Stroke Res Program, Boston, MA 02114 USAMassachusetts Gen Hosp, Hemorrhag Stroke Res Program, Boston, MA 02114 USA
FitzMaurice, Emily
Wendell, Lauren
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Massachusetts Gen Hosp, Hemorrhag Stroke Res Program, Boston, MA 02114 USAMassachusetts Gen Hosp, Hemorrhag Stroke Res Program, Boston, MA 02114 USA
Wendell, Lauren
Goldstein, Joshua N.
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Massachusetts Gen Hosp, Dept Emergency Med, Boston, MA 02114 USAMassachusetts Gen Hosp, Hemorrhag Stroke Res Program, Boston, MA 02114 USA
Goldstein, Joshua N.
Greenberg, Steven M.
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Massachusetts Gen Hosp, Hemorrhag Stroke Res Program, Boston, MA 02114 USAMassachusetts Gen Hosp, Hemorrhag Stroke Res Program, Boston, MA 02114 USA
Greenberg, Steven M.
Rosand, Jonathan
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Massachusetts Gen Hosp, Hemorrhag Stroke Res Program, Boston, MA 02114 USA
Massachusetts Gen Hosp, Ctr Human Genet Res, Boston, MA 02114 USAMassachusetts Gen Hosp, Hemorrhag Stroke Res Program, Boston, MA 02114 USA