Serum soluble interleukin-2 receptor in eosinophilia

被引:5
|
作者
Kaito, K
Otsubo, H
Ogasawara, Y
Kimura, H
Kurihara, E
Koike, M
Aiso, M
Kobayashi, M
机构
[1] Jikei Univ Hosp, Cent Clin Lab, Minato Ku, Tokyo 1058471, Japan
[2] Jikei Univ, Sch Med, Dept Internal Med, Div Hematol & Oncol, Tokyo, Japan
关键词
eosinophilia; IgE; interleukin-2; receptor; soluble;
D O I
10.1159/000067274
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
The relationship between soluble interleukin-2 receptor (sIL-2R) levels and clinical characteristics was evaluated in patients with eosinophilia. Thirty-eight out of 60 patients showed sIL-2R levels of more than 800 U/ml. In these patients, sIL-2R was closely related to the eosinophil count, but not the IgE level. Their underlying diseases were heterogeneous, including neoplasms and collagen diseases. In patients with lower sIL-2R levels, there was no relationship to the eosinophil count, but sIL-2R was correlated with the IgE level. These findings indicate that patients with eosinophilia and higher sIL-2R levels tend to have underlying diseases other than allergy, and might be more severely ill than patients with lower sIL-2R levels. sIL-2R may be a good marker for evaluating patients with eosinophilia, as an indicator of the probable etiology and severity of their diseases. Copyright (C) 2003 S. Karger AG, Basel.
引用
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页码:23 / 28
页数:6
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